Mechanical interventricular dependency supports hemodynamics in tako-tsubo cardiomyopathy

Journal of Thoracic Disease
Juan LeiKan Liu

Abstract

Although morphological abnormalities of the heart appear to be remarkable, most patients with tako-tsubo cardiomyopathy (TTC) remain clinically stable. We investigate real time changes in the left ventricular (LV) and right ventricular (RV) mechanics and function to explore the mechanism to preserve hemodynamics. With deformation and Doppler echocardiography, we evaluated myocardial mechanics and ventricular function/hemodynamics simultaneously in 103 consecutive TTC patients admitted from 01/01/2008 through 12/31/2015. The coronary angiography and left ventriculography were performed to rule out culprit coronary artery stenosis (CAS). We included 66 patients in a control group with matched age, sex, and risk factors for coronary artery disease (CAD), and 41 patients in a group of myocardial infarction induced cardiogenic shock, who required circulatory supporting devices to maintain hemodynamic stability. Although systolic myocardial strain in most of the LV segments was significantly impaired, 4 basal LV segments remained functionally active during acute stage of TTC. The impairment in the myocardial strain of the RV apex could extend to the middle segments, but basal RV systolic strain was also preserved. Despites comparable...Continue Reading

Citations

Jun 9, 2020·European Heart Journal. Acute Cardiovascular Care·Juan LeiKan Liu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.

Related Papers

Circulation Journal : Official Journal of the Japanese Circulation Society
Kenya SakaiToshio Nakanishi
European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
Patrick MeimounAnne Luycx-Bore
European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
Patrick MeimounChristophe Tribouilloy
© 2022 Meta ULC. All rights reserved