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Mechanical plasticity of the ECM directs invasive branching morphogenesis in human mammary gland organoids

bioRxiv

Nov 29, 2019

Benedikt BuchmannAndreas Bausch

Abstract

Although branching morphogenesis is central for organogenesis in diverse organs, the underlying self-organizing principles have yet to be identified. Here, we show that invasive branching morphogenesis in human mammary organoids relies on an intricate tension-driven feedback mechanism, ...read more

Mentioned in this Paper

Morphogenesis of a Branching Structure
Organogenesis
Neuronal Plasticity
Organoids
Bud Outgrowth Involved in Lung Branching
Collagen
Mammary Gland
Extracellular Matrix
Organ
Loops
18
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Mechanical plasticity of the ECM directs invasive branching morphogenesis in human mammary gland organoids

bioRxiv

Nov 29, 2019

Benedikt BuchmannAndreas Bausch

DOI: 10.1101/860015

Abstract

Although branching morphogenesis is central for organogenesis in diverse organs, the underlying self-organizing principles have yet to be identified. Here, we show that invasive branching morphogenesis in human mammary organoids relies on an intricate tension-driven feedback mechanism, ...read more

Mentioned in this Paper

Morphogenesis of a Branching Structure
Organogenesis
Neuronal Plasticity
Organoids
Bud Outgrowth Involved in Lung Branching
Collagen
Mammary Gland
Extracellular Matrix
Organ
Loops
18

Similar Papers Found In These Feeds

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Paper Details
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