PMID: 38671Sep 1, 1979

Mechanical properties and functions of the myoepithelium in the eccrine sweat gland

The American Journal of Physiology
K SatoM Kobayashi

Abstract

Contractile properties of an isolated segment of the secretory coil of the monkey palm eccrine sweat gland were studied in vitro with a transducer. Contraction of up to 10 mgf was induced with acetylcholine but not with alpha or beta adrenergic agonists, caffeine, prostaglandin E1, or by a calcium ionophore A23187. Other features included K+ contracture, staircase effect, poor extensibility, length-tension relationship with a peak tensile response at 115--120% of the resting length, and requirement of Ca2+. The function of myoepithelium is unlikely to expulse the preformed sweat because the amount of preformed sweat is small, K+-contracture failed to expulse sweat, and because myoepithelial contraction was not induced by such stimulants of sweat secretion as A23187, phenylephrine, isoproterenol, and prostaglandin E1. The maximal transverse tension of 20 mgf during acetylcholine stimulation under resting tension was calculated to support the luminal hydrostatic pressure of approximately 500 mmHg. Thus the function of the myoepithelium may be to render structural support for the secretory epithelium.

Citations

Jan 1, 1986·Pflügers Archiv : European journal of physiology·K Sato
Oct 11, 2016·The Journal of Clinical Investigation·Axel R ConcepcionStefan Feske
Jan 6, 2018·Journal of Molecular Histology·Margherita SistoSabrina Lisi
Sep 1, 1983·Veterinary Research Communications·A Warner, I G Mayhew
Feb 19, 2002·Laboratory Investigation; a Journal of Technical Methods and Pathology·Dimitra BeroukasSally A Waterman
Oct 8, 2016·Cellular and Molecular Life Sciences : CMLS·Vinciane Saint-Criq, Michael A Gray
Jul 23, 2018·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Adam LoavenbruckWilliam Kennedy
Apr 1, 1984·The British Journal of Dermatology·I MontgomeryR M MacKie
Nov 7, 2006·Veterinary Dermatology·David McEwan JenkinsonDouglas L Bovell
Jan 5, 2001·Acta Neurologica Scandinavica. Supplementum·O SjaastadJ Bathen
Nov 14, 2002·Laboratory Investigation; a Journal of Technical Methods and Pathology·Dimitra BeroukasSally A Waterman

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