PMID: 15347989Sep 7, 2004Paper

Mechanical properties of sintered hydroxyapatite and tricalcium phosphate ceramic

Journal of Materials Science. Materials in Medicine
D S MetsgerD W Foreman

Abstract

The ultimate values for compressive strength, Young's modulus, and toughness of cylindrical specimens of unitary aspect ratios and uniform grain-size distributions were extrapolated for hydroxyapatite (HAP) to 70 MPa, 9.2 GPa, and 0.36 J cm(-3), and for tricalcium phosphate (TCP), to 315 MPa, 21 GPa, and 2.34 J cm(-3). For total volume porosities of 50%, the corresponding values were determined: for HAP, 9.3 MPa, 1.2 GPa, 0.042 J cm(-3), for TCP, 13 MPa, 1.6 GP, 0.077 J cm(-3). Porosities of HAP specimens ranged from 3%-50%; TCP from 10%-70%. Two pore-size distributions were employed. Exponential dependencies of the mechanical properties were found upon porosity (p < 0.0001). No differences in measured mechanical properties, as determined in compression, could be attributed to pore size. The superiority of TCP increases with density and suggests that a larger or more selective pore-size distribution could be effectively employed in TCP biological implants. This work also suggests the dominant role of secondary calcium phosphates in increasing compressive strengths.

Citations

Jul 25, 2012·Journal of Biomedical Materials Research. Part a·Krzysztof W LuczynskiChristian Hellmich
Sep 4, 2012·International Journal for Numerical Methods in Biomedical Engineering·J JonvauxE Budyn
Jan 18, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Isis C EncarnaçãoRicardo S Magini
Oct 19, 2017·Journal of Biomedical Materials Research. Part a·Joseph B VellaDanielle S W Benoit
Jan 12, 2002·Journal of Biomedical Materials Research·J E BarraletJ C Knowles
May 22, 2008·Tissue Engineering. Part a·Ander AbarrategiJosé Luís López-Lacomba
Jan 11, 2007·Journal of Materials Science. Materials in Medicine·Himesh A Bhatt, Samar J Kalita
Apr 16, 2015·Annals of Medicine·Qian PengZhiwei Peng
Dec 10, 2015·Journal of Biomedical Materials Research. Part a·Devis BellucciValeria Cannillo
May 29, 2007·Biomechanics and Modeling in Mechanobiology·J A Sanz-HerreraM Doblare
Nov 15, 2013·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·S EtcheparebordeM Balligand
Feb 25, 2006·Journal of Biomedical Materials Research. Part a·Jennifer G DellingerRussell D Jamison

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