PMID: 9161898May 1, 1997Paper

Mechanical simulation of cardiac function by means of pulsatile blood pumps

Journal of Cardiothoracic and Vascular Anesthesia
G Wright

Abstract

After a review of the theoretical and experimental background, a history of the development of pulsatile blood pumps is presented with an attempt to understand the underlying rationale. The case for the use of pumps that simulate normal cardiac function is made by considering cardiovascular hemodynamics, the function of arterial baro-receptors, hemodynamic energy and power, tissue fluid movement, and lymph formation and flow. The pulsatile output of the heart and mechanical pumps is described in units of power and the load that they work against as a complex impedance. Many pulsatile pumps have been designed and developed for research, but few have been used during cardiac operations on human patients. The evidence in favor of using pulsatile flow for cardiopulmonary bypass is strong, but major problems have been identified such as the lack of a satisfactory definition of pulsatile flow and technical difficulties resulting from impedance mismatches in clinical applications.

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Citations

May 18, 2013·Annals of Biomedical Engineering·Stefanos E DiamantourosStefan Jockenhoevel
Jun 23, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Akif UndarJohn L Myers
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Salvatore AgatiAkif Undar
Aug 3, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Bingyang Ji, Akif Undar
Feb 28, 2004·Journal of Biomechanical Engineering·F Carroll DoughertyMary I Townsley
Oct 23, 2013·Heart, Lung & Circulation·Gökhan LafçOmer Faruk Cicek
Apr 26, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Nick J KoningChrista Boer
Nov 29, 2011·Computer Methods and Programs in Biomedicine·K T MoorheadT Desaive
Sep 21, 2016·Artificial Organs·Matthias KleinheyerWilliam E Cohn
Aug 5, 2010·Critical Care Medicine·Christopher W MastropietroAshok P Sarnaik
Jan 26, 2018·Journal of Cardiovascular Development and Disease·Massimo Capoccia
Feb 10, 2000·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·A Undar, C D Fraser
Jul 1, 2021·Computational and Mathematical Methods in Medicine·Luciano CurcioAndrea De Gaetano

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