Mechanical Thrombectomy in Elderly Stroke Patients with Mild-to-Moderate Baseline Disability

Interventional Neurology
Diana E SlawskiMouhammad A Jumaa

Abstract

The number of elderly patients suffering from ischemic stroke is rising. Randomized trials of mechanical thrombectomy (MT) generally exclude patients over the age of 80 years with baseline disability. The aim of this study was to understand the efficacy and safety of MT in elderly patients, many of whom may have baseline impairment. Between January 2015 and April 2017, 96 patients ≥80 years old who underwent MT for stroke were selected for a chart review. The data included baseline characteristics, time to treatment, the rate of revascularization, procedural complications, mortality, and 90-day good outcome defined as a modified Rankin Scale (mRS) score of 0-2 or return to baseline. Of the 96 patients, 50 had mild baseline disability (mRS score 0-1) and 46 had moderate disability (mRS score 2-4). Recanalization was achieved in 84% of the patients, and the rate of symptomatic hemorrhage was 6%. At 90 days, 34% of the patients had a good outcome. There were no significant differences in good outcome between those with mild and those with moderate baseline disability (43 vs. 24%, p = 0.08), between those aged ≤85 and those aged > 85 years (40.8 vs. 26.1%, p = 0.19), and between those treated within and those treated beyond 8 h (39...Continue Reading

Citations

Jan 28, 2020·The Neuroradiology Journal·Saminderjit KularSanjoy Nagaraja
Jan 11, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Younsu AhnWoong Yoon
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Mar 26, 2019·Stroke; a Journal of Cerebral Circulation·Ajay MalhotraJoseph Schindler
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Feb 9, 2021·Frontiers in Neurology·Nathanael MateiJohn H Zhang
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