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Mechanical trapping of the nucleus on micropillared surfaces inhibits the proliferation of vascular smooth muscle cells but not cervical cancer HeLa cells

Journal of Biomechanics

Jun 10, 2015

Kazuaki NagayamaTakeo Matsumoto

Abstract

The interaction between cells and the extracellular matrix on a topographically patterned surface can result in changes in cell shape and many cellular functions. In the present study, we demonstrated the mechanical deformation and trapping of the intracellular nucleus using polydimethy...read more

Mentioned in this Paper

Lamins
Muscle, Smooth, Vascular
Pathologic Cytolysis
Study
Extracellular
Nuclear Lamina
Science of Morphology
Protoplasm
Memory Impairment
Cell Division
Paper Details
References
  • References30
  • Citations4
123
  • References30
  • Citations4
1

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Mechanical trapping of the nucleus on micropillared surfaces inhibits the proliferation of vascular smooth muscle cells but not cervical cancer HeLa cells

Journal of Biomechanics

Jun 10, 2015

Kazuaki NagayamaTakeo Matsumoto

PMID: 26054426

DOI: 10.1016/j.jbiomech.2015.05.004

Abstract

The interaction between cells and the extracellular matrix on a topographically patterned surface can result in changes in cell shape and many cellular functions. In the present study, we demonstrated the mechanical deformation and trapping of the intracellular nucleus using polydimethy...read more

Mentioned in this Paper

Lamins
Muscle, Smooth, Vascular
Pathologic Cytolysis
Study
Extracellular
Nuclear Lamina
Science of Morphology
Protoplasm
Memory Impairment
Cell Division

Similar Papers Found In These Feeds

Osteosarcoma

Osteosarcoma is the most common primary bone malignancy diagnosed in children and young adults and has a high propensity for local invasion and distant metastasis. Here is the latest research.

Nuclear Envelope Dynamics

The nuclear envelope provides barrier between the nucleus and cytoplasm. It plays a key role in transport function and nuclear growth, organization, and integrity. Discover the latest research on nuclear envelope dynamics here.

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