Mechanical ventilation in patients with acute neurological disease: survival and functional outcome

Revista médica de Chile
Enrique NoreroGuillermo Bugedo

Abstract

The need of mechanical ventilation among patients with acute neurological diseases is considered a poor prognostic sign. To determine the mortality and functional recovery of neurological patients requiring mechanical ventilation. Prospective study of 77 patients (42 men, age 54+/-19 years, with 11+/-4 points of Glasgow coma scale (GCS), 61% with cerebrovascular disease), that were admitted to the intensive care unit with neurological disease and that required mechanical ventilation. Functional recovery was assessed at 18 months with Glasgow outcome scale (GOS) and Barthel index. Thirty percent of patients died during follow up. Among surviving patients, 47% had a good recovery or moderate disability, and 74% had a Barthel index equal to or over 70. Arterial hypertension, age over 70 and mechanical ventilation longer than 6 days were associated with bad functional prognosis. Neurological patients requiring mechanical ventilation had a lower mortality than previously reported, and half of the survivors have an independent life. This study supports intensive care management in this group of patients.

Citations

Mar 8, 2011·Critical Care Medicine·Paolo PelosiUNKNOWN Ventila Study Group

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