Mechanical versus manual chest compressions in the treatment of in-hospital cardiac arrest patients in a non-shockable rhythm: a randomised controlled feasibility trial (COMPRESS-RCT).

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Keith CouperCOMPRESS-RCT collaborators

Abstract

Mechanical chest compression devices consistently deliver high-quality chest compressions. Small very low-quality studies suggest mechanical devices may be effective as an alternative to manual chest compressions in the treatment of adult in-hospital cardiac arrest patients. The aim of this feasibility trial is to assess the feasibility of conducting an effectiveness trial in this patient population. COMPRESS-RCT is a multi-centre parallel group feasibility randomised controlled trial, designed to assess the feasibility of undertaking an effectiveness to compare the effect of mechanical chest compressions with manual chest compressions on 30-day survival following in-hospital cardiac arrest. Over approximately two years, 330 adult patients who sustain an in-hospital cardiac arrest and are in a non-shockable rhythm will be randomised in a 3:1 ratio to receive ongoing treatment with a mechanical chest compression device (LUCAS 2/3, Jolife AB/Stryker, Lund, Sweden) or continued manual chest compressions. It is intended that recruitment will occur on a 24/7 basis by the clinical cardiac arrest team. The primary study outcome is the proportion of eligible participants randomised in the study during site operational recruitment hours...Continue Reading

Associated Clinical Trials

References

Jan 20, 2005·JAMA : the Journal of the American Medical Association·Benjamin S AbellaLance B Becker
Dec 1, 2012·Journal of Clinical Epidemiology·Kim Cocks, David J Torgerson
Apr 22, 2014·Resuscitation·Jerry P NolanUNKNOWN National Cardiac Arrest Audit
Sep 26, 2014·Circulation·Ian G StiellUNKNOWN Resuscitation Outcomes Consortium Investigators
Jan 8, 2015·Critical Care Medicine·Ahamed H IdrisUNKNOWN Resuscitation Outcomes Consortium Investigators
Apr 19, 2015·Current Opinion in Critical Care·Keith CouperGavin D Perkins
Jul 18, 2015·Critical Care Medicine·Keith CouperUNKNOWN Cardiopulmonary Resuscitation Quality Improvement Initiative Collaborators
Feb 27, 2016·Emergency Medicine Journal : EMJ·Helen PocockSimon Gates
Apr 8, 2016·BMJ : British Medical Journal·Keith Couper, Gavin D Perkins
Nov 21, 2016·Resuscitation·Claire HawkesUNKNOWN OHCAO collaborators
Feb 10, 2018·Resuscitation·Lars W AndersenMichael W Donnino

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Clinical Trials Mentioned

ISRCTN08233942

Software Mentioned

COMPRESS

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