Mechanism of fulminant pulmonary edema caused by enterovirus 71

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Shang Jyh KaoHsing I Chen

Abstract

Pulmonary edema (PE) may occur with enterovirus 71 (EV71) infection. We monitored arterial pressure (AP) and heart rate (HR) in patients with EV71 infection and analyzed the variability of AP and HR. Sympathetic activity, AP, and HR increased with respiratory stress. Thereafter, parasympathetic activity increased with decreases in AP and HR. The lungs showed edema with inducible nitric oxide synthase (iNOS) expression. Destruction of the medial, ventral, and caudal medulla may lead to sympathetic overactivation, causing blood to shift to the lungs. The pathogenesis of PE may also involve iNOS and nitric oxide.

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Citations

Jan 9, 2010·Epidemiology and Infection·S S Y WongK Y Yuen
Mar 1, 2006·Critical Care Medicine·Hsing I ChenShang-Jyh Kao
Jan 25, 2008·Critical Care Medicine·Demeral David LiuHsing I Chen
Sep 20, 2007·Journal of Cardiovascular Pharmacology·Shang-Jyh KaoHsing I Chen
Feb 2, 2010·The Pediatric Infectious Disease Journal·Ta-Chung LeeKow-Tong Chen
Feb 28, 2008·The Journal of Trauma·Shang-Jyh Kao, Hsing I Chen
Feb 1, 2006·Clinical and Experimental Pharmacology & Physiology·Shang Jyh KaoHsing I Chen
Jan 5, 2007·Clinical and Experimental Pharmacology & Physiology·Demeral D LiuHsing I Chen
Feb 28, 2007·Clinical and Experimental Pharmacology & Physiology·Chain Fa SuHsing I Chen
Apr 19, 2007·Clinical and Experimental Pharmacology & Physiology·Shang-Jyh KaoHsing I Chen
May 3, 2007·Medicine and Science in Sports and Exercise·Hsing I ChenChia-Chih Lin
Nov 7, 2009·Emerging Infectious Diseases·Sophie ValletPascale Marcorelles
Jan 14, 2016·Viruses·Léna Royston, Caroline Tapparel
Mar 30, 2006·The Kaohsiung Journal of Medical Sciences·Yung-Hsiang HsuHui-Hua Yang
Nov 28, 2015·Viruses·Hsing-I Huang, Shin-Ru Shih
Oct 8, 2014·Journal of Neuropathology and Experimental Neurology·Soon Hao TanKum Thong Wong
Sep 21, 2007·Clinical and Experimental Pharmacology & Physiology·Yen Chin LiuHsing I Chen
Aug 30, 2008·Pathology·Yung-Hsiang Hsu, Hsing I Chen
Jun 15, 2007·Pathology·Hsing I ChenYung-Hsiang Hsu
Apr 23, 2008·Pathology·Yung-Hsiang Hsu, Hsing I Chen
Oct 31, 2006·Pulmonary Pharmacology & Therapeutics·I Chun ChuangHsing I Chen
Jul 25, 2006·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Shih-Min WangChing-Chuan Liu
May 23, 2006·Pulmonary Pharmacology & Therapeutics·Chia-Hsiang ChuHsing I Chen
Sep 8, 2012·Clinical & Developmental Immunology·Shih-Min WangChing-Chuan Liu
Sep 13, 2016·International Journal of Environmental Research and Public Health·Ping-Chin ChangKow-Tong Chen
Apr 4, 2012·World Journal of Critical Care Medicine·Chain-Fa SuHsing I Chen
May 11, 2011·Laboratory Investigation; a Journal of Technical Methods and Pathology·Ying ZhangQihan Li

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