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Mechanism of initiation and repression of in vitro transcription of the lac operon of Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America

Aug 1, 1971

L Eron, R E Block

PMID: 4331560

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Abstract

A cyclic AMP-binding protein (CAP protein), cyclic AMP, and RNA polymerase holoenzyme are shown to initiate lac transcription at the lac promoter. Lac repressor appears to control transcription by preventing RNA polymerase and/or CAP protein from binding to the lac promoter. Results sup...read more

Mentioned in this Paper

Operon
Genetic Template
Mutation Abnormality
RNA Nucleotidyltransferases
Transcription Initiation
Genomic Hybridization
Genes, Regulator
Lac Operon
Promoter
Genetic Code
Paper Details
References
  • References17
  • Citations82
12
  • References17
  • Citations82
12345...

Mechanism of initiation and repression of in vitro transcription of the lac operon of Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America

Aug 1, 1971

L Eron, R E Block

PMID: 4331560

DOI:

Abstract

A cyclic AMP-binding protein (CAP protein), cyclic AMP, and RNA polymerase holoenzyme are shown to initiate lac transcription at the lac promoter. Lac repressor appears to control transcription by preventing RNA polymerase and/or CAP protein from binding to the lac promoter. Results sup...read more

Mentioned in this Paper

Operon
Genetic Template
Mutation Abnormality
RNA Nucleotidyltransferases
Transcription Initiation

Related Papers

Paper Details
References
  • References17
  • Citations82
12
  • References17
  • Citations82
12345...

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