Dec 14, 2006

Mechanism of neurophysiological treatment of amblyopia using functional magnetic resonance imaging

Yan ke xue bao = Eye science
Guangming LuLin Li


To research the mechanism of neurophysiological treatment of amblyopia by observing the visual cortex activation under rotating grating stimulus with functional magnetic resonance imaging (MRI), and identify the components of the activation. Nine healthy volunteers were examined using gradient-recalled echo and echo-planar imaging (GRE-EPI) pulse sequence performed at the 1.5 Tesla MRI scanner. In the block designing, rotating grating, stationary grating and luminance were plotted as task states, stationary grating, luminance and darkness as control states, respectively. The tasks of stimuli included 6 steps. Imaging processing and statistical analysis were carried out off-line using statistical parametric mapping (SPM99) software in single-subject. Some individual areas of visual cortex were activated by various stimuli information supplied by rotating grating. The strong activation in the middle of occipital lobe related to the stimuli of luminance, bilateral activation of Brodmann's 19th area related to visual motion perception, and the mild activation in the middle of occipital lobe related to form perception. The plotting of control state is important in bock design. The effective visual information of rotating grating inc...Continue Reading

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Mentioned in this Paper

Occipital Lobe
Visual Perception
Entire Occipital Lobe
Motion Perception
Entire Brodmann Areas 17 (Striate Cortex),18 (Parastriate Cortex) and 19 (Peristriate Cortex) of Occipital Lobe
Magnetization Transfer Contrast Imaging
Malignant Neoplasm of Occipital Lobe
Visual Cortex
Echo-Planar Imaging

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