Mechanism of protective effect of energostim during catalepsy produced by single treatment with trifluoperazine

Bulletin of Experimental Biology and Medicine
E A ChikobavaG V Sukoyan

Abstract

NAD, cytochrome c, and energostim modulated the fluorescence emission spectrum of trifluoperazine in the solution and in microsomal suspension. The data suggest that NAD and energostim modify structural and conformational characteristics of the dopamine receptor-trifluoperazine complex. These changes probably underlie the anticataleptic effect of energostim.

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