Mechanisms and factors associated with gastrointestinal symptoms in patients with diabetes mellitus

Jornal de pediatria
Mônica Loureiro Celino Rodrigues, Maria Eugênia Farias Almeida Motta

Abstract

To present the main mechanisms that cause gastrointestinal symptoms in patients with diabetes mellitus, their frequency, and controversies as to their occurrence in children and adolescents. Non-systematic review of the literature conducted in the MEDLINE/PubMed and SciELO databases (1983-2011), as well as relevant book chapters. The most relevant and up-to-date articles on the topic were selected. Prevalence of diabetes mellitus has been increasing over the years in many countries. The complications caused by this disease in the digestive system, such as gastrointestinal symptoms (nausea, vomiting, abdominal pain, heartburn, dysphagia, constipation, diarrhea, and fecal incontinence) are well known. The pathogenesis of changes in the gastrointestinal functions in patients with diabetes mellitus is still being investigated at the same time as the role of the enteric nervous system and its neurotransmitters has gained significance. As a consequence of the complications in the digestive system, which damage the enteric nervous system, patients with diabetes mellitus may have specific gastrointestinal motility disorders, some of which may be of great relevance, such as diabetic gastroparesis, constipation, and diarrhea. Gastrointes...Continue Reading

Citations

Jun 8, 2013·World Journal of Gastroenterology : WJG·Yun WangLin Lin
Jul 11, 2014·World Journal of Gastroenterology : WJG·Xia ChenHong-Xian Zhao
Jul 12, 2017·World Journal of Diabetes·Mirabella ZhaoJingbo Zhao
Dec 29, 2013·Digestive Diseases and Sciences·Catchia Hermes-UlianaJacqueline Nelisis Zanoni
Dec 31, 2015·World Journal of Gastroenterology : WJG·Mei ZhangDan-Dan Zhao

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