Mechanisms and regulation of epithelial phosphate transport in ruminants: approaches in comparative physiology

Pflügers Archiv : European journal of physiology
A S Muscher-Banse, G Breves

Abstract

Ruminants have a unique utilization of phosphate (Pi) based on the so-called endogenous Pi recycling to guarantee adequate Pi supply for ruminal microbial growth and for buffering short-chain fatty acids. Large amounts of Pi enter the gastrointestinal tract by salivary secretion. The high saliva Pi concentrations are generated by active secretion of Pi from blood into primary saliva via basolateral sodium (Na+)-dependent Pi transporter type II. The following subsequent intestinal absorption of Pi is mainly carried out in the jejunum by the apical located secondary active Na+-dependent Pi transporters NaPi IIb (SLC34A2) and PiT1 (SLC20A1). A reduction in dietary Pi intake stimulates the intestinal Pi absorption by increasing the expression of NaPi IIb despite unchanged plasma 1,25-dihydroxyvitamin D3 concentrations, which modulate Pi homeostasis in monogastric species. Reabsorption of glomerular filtrated plasma Pi is mainly mediated by the Pi transporters NaPi IIa (SLC34A1) and NaPi IIc (SLC34A3) in proximal tubule apical cells. The expression of NaPi IIa and the corresponding renal Na+-dependent Pi capacity were modulated by high dietary phosphorus (P) intake in a parathyroid-dependent manner. In response to reduced dietary Pi...Continue Reading

References

Mar 30, 1976·Pflügers Archiv : European journal of physiology·N HoffmannR Kinne
May 1, 1979·The Journal of Physiology·M C Neville, M Peaker
Jun 1, 1978·The Journal of Physiology·I R Fleet, M Peaker
Jan 1, 1990·Comparative Biochemistry and Physiology. A, Comparative Physiology·B SchröderE Pfeffer
Jan 1, 1989·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·S P Shirazi-BeecheyR B Beechey
Jan 1, 1989·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·H Jungbluth, U Binswanger
Apr 1, 1988·Journal of Bioenergetics and Biomembranes·S P Shirazi-BeecheyR B Beechey
Jul 1, 1986·Quarterly Journal of Experimental Physiology : an International Journal of the Physiological Society·E M MaunderA D Care
May 1, 1980·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M Peterlik, R H Wasserman
Mar 1, 1982·Journal of Dairy Science·L Eriksson, M Valtonen
Aug 1, 1995·Zentralblatt für Veterinärmedizin. Reihe A·B SchröderG Breves
Feb 1, 1995·Biochemical Society Transactions·J M ShillingfordR B Beechey
Nov 1, 1995·The British Journal of Nutrition·B SchröderG Breves
Apr 1, 1996·Kidney International·S P Shirazi-BeecheyW Buchan
Jan 1, 1996·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·B Schröder, G Breves
Jul 1, 1998·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·J FickelG Breves
Jul 3, 1998·Biochemical Society Transactions·I S WoodS P Shirazi-Beechey
Jul 22, 1998·Journal of Bioenergetics and Biomembranes·J BiberI Forster
Jul 23, 1998·Zentralblatt für Veterinärmedizin. Reihe A·I WidiyonoG Breves
Nov 25, 1998·Proceedings of the National Academy of Sciences of the United States of America·H HilfikerJ Biber
Oct 4, 2000·Physiological Reviews·H MurerJ Biber
Nov 18, 2000·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·B SchröderK Huber
Feb 24, 2001·Annals of the New York Academy of Sciences·K HuberG Breves
Jul 18, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Korinna HuberGerhard Breves
Oct 22, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Korinna HuberGerhard Breves
May 17, 2003·Pflügers Archiv : European journal of physiology·Heini MurerJürg Biber
Oct 21, 2006·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Korinna HuberGerhard Breves
Dec 2, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Korinna HuberGerhard Breves
May 23, 2007·Acta Physiologica·D H SolomonR J Wilkins
Jun 28, 2007·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Daniel H SolomonJoseph A Browning
Jan 23, 2008·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Alexandra MuscherKorinna Huber
May 22, 2008·Journal of Animal Physiology and Animal Nutrition·A MuscherK Huber
Sep 2, 2008·Pflügers Archiv : European journal of physiology·J BiberH Murer
Jan 1, 1991·Nutrition Research Reviews·G Breves, B Schröder
Apr 20, 2010·The Journal of Steroid Biochemistry and Molecular Biology·Alexandra Muscher, Korinna Huber
Mar 24, 2011·Journal of Dairy Science·A P FooteJ P Muir
Mar 30, 2011·The British Journal of Nutrition·Alexandra S MuscherKorinna Huber

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Citations

Dec 14, 2018·Pflügers Archiv : European journal of physiology·Eleanor Lederer, Carsten A Wagner
Dec 21, 2018·Pflügers Archiv : European journal of physiology·Heini MurerAndreas Werner
Oct 9, 2020·Animals : an Open Access Journal From MDPI·Keren E DittmerSara Azarpeykan
Dec 10, 2020·International Journal of Molecular Sciences·Marco Antonio Lacerda-AbreuJose Roberto Meyer-Fernandes

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