Mechanisms and risk factors for infection of pulmonary artery catheters and introducer sheaths in cancer patients admitted to an intensive care unit

The Journal of Hospital Infection
F BlotG Nitenberg

Abstract

Pulmonary artery catheters (PACs) are typically inserted for short periods, and the extra-luminal route is assumed to be the overriding source of contamination and/or infection. Our aim was to assess the incidence of PAC and introducer colonization in cancer patients, and to study the mechanisms and risk factors for infection. Patients with a Swan-Ganz catheter admitted to an intensive care unit were prospectively analyzed over 14 months. As soon they were no longer necessary, PACs and introducer sheaths were removed and cultured. We recorded the mean duration of placement, the number of times PACs were handled and the site of insertion. Seventy-nine catheters were inserted in 68 patients. The median (range) duration was three days (0-10) for PACs, and 3.6 days (0-18) for introducers. PAC and/or percutaneous introducer sheath colonization was diagnosed in seven patients (8.9%), but in only one case were both colonized. Colonization rates were 15.5 per 1000 days for PACs and 14.1 per 1000 days for introducers. Introducers were mainly colonized before the 5th day, while PACs were mainly colonized after the 5th day. No PAC or introducer-related local infection or bacteraemia was diagnosed. Colonization was more frequent on cathete...Continue Reading

References

Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
Sep 1, 1987·Chest·L PasseriniE G King
May 1, 1987·Archives of Internal Medicine·C Brun-BuissonM Rapin
Dec 1, 1985·Annals of Surgery·W A KnausJ E Zimmerman
Apr 1, 1994·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·I I RaadG P Bodey
Jan 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J VallésA Artigas
Jun 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F BlotB Escudier
Dec 24, 1997·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·P LjungmanO Ringdén

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Citations

Sep 23, 2006·Critical Care : the Official Journal of the Critical Care Forum·Joseph V DiCarloSteven R Alexander
Apr 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC)
Apr 29, 2011·American Journal of Infection Control·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Apr 19, 2005·Intensive Care Medicine·Abbas HarbFrançois Blot
Feb 25, 2003·Cancer Control : Journal of the Moffitt Cancer Center·Gianluigi FerrettiSandro Barni

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