Jun 7, 2005

Mechanisms for selection of basic motor programs--roles for the striatum and pallidum

Trends in Neurosciences
Sten GrillnerMartin A Wikström


The nervous system contains a toolbox of motor programs in the brainstem and spinal cord--that is, neuronal networks designed to handle the basic motor repertoire required for survival, including locomotion, posture, eye movements, breathing, chewing, swallowing and expression of emotions. The neural mechanisms responsible for selecting which motor program should be recruited at a given instant are the focus of this review. Motor programs are kept under tonic inhibition by GABAergic pallidal neurons (the output nuclei of the basal ganglia). The motor programs can be relieved from pallidal inhibition through activation of striatal neurons at the input stage of the basal ganglia. It is argued that the striatum has a prominent role in selecting which motor program should be called into action.

  • References29
  • Citations230


Mentioned in this Paper

Examination of Reflexes
Cortex Bone Disorders
Adrenal Cortex Diseases
Entire Brainstem
Globus Pallidus
Projections and Predictions

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Related Papers

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Mark D HumphriesKevin N Gurney
Journal of Neurophysiology
Okihide HikosakaHiroyuki Nakahara
© 2020 Meta ULC. All rights reserved