Mechanisms of age-related cognitive change and targets for intervention: social interactions and stress.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
William S KremenRobert S Wilson

Abstract

The effects of biological and physical factors on cognitive aging are widely studied. Less is known about the role of psychosocial factors such as stress and social relationships for cognitive functioning. Speakers in Session IV of the Summit focused on possible mechanisms linking social interactions and stressful experiences to cognitive changes with aging. Elevated cortisol, repetitive thinking, negative emotions, neuroticism, chronic stress, and early life adversity were negatively associated with memory and other cognitive dimensions in later life. In contrast, supportive social relationships were found to be positively related to cognitive functioning. Some evidence was provided for multidirectional, causal relationships involving stress and negative affect as both antecedents and consequences of cognitive decline. The findings contribute to understanding the potential underlying causal processes linking psychosocial factors and cognitive aging with a developmental focus on the etiology of declines and onset of cognitive impairments. This work provides an important foundation for future research to identify modifiable factors and to design interventions to minimize cognitive declines and optimize cognitive health in adulth...Continue Reading

References

Mar 19, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jens C PruessnerAlain Dagher
Sep 7, 2006·Psychology and Aging·Robert S StawskiJoshua M Smyth
Sep 16, 2006·Neuroepidemiology·Robert S WilsonDavid A Bennett
Jan 25, 2007·Psychosomatic Medicine·Robert S WilsonDavid A Bennett
Mar 9, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Claudia BussJens C Pruessner
Jun 15, 2007·Neurology·R S WilsonD A Bennett
Nov 10, 2007·Psychosomatic Medicine·Suzanne PieperJulian F Thayer
Apr 9, 2008·Archives of General Psychiatry·Robert S WilsonDavid A Bennett
Dec 11, 2008·Annals of Neurology·Hélène AmievaJean François Dartigues
Aug 21, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Michelle C CarlsonLinda P Fried
Jan 23, 2010·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Margie E LachmanPatricia A Tun
Jun 16, 2010·Psychology and Aging·Robert S StawskiChristopher B Rosnick
Sep 17, 2010·Neurology·R S WilsonD A Bennett
Mar 24, 2011·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Robert S WilsonDavid A Bennett
May 25, 2011·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Carol E FranzWilliam S Kremen
Jul 16, 2011·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Stefan Agrigoroaei, Margie E Lachman
Jul 16, 2011·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Avron Spiro, Christopher B Brady

❮ Previous
Next ❯

Citations

Feb 22, 2014·Psychodynamic Psychiatry·Daniel A Plotkin
Apr 15, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Yukari YamadaEva Topinkova
Jul 23, 2015·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Andrzej Brodziak
Nov 14, 2013·Journal of the American Geriatrics Society·Jacqueline KerrKatie Crist
Mar 18, 2016·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Laura A RabinWilliam B Barr
Dec 7, 2013·Aging Cell·Paul A AdlardRobert A Cherny
Jan 1, 2015·Behavioural Brain Research·Barry S OkenWayne Wakeland
Mar 25, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Irina Chamine, Barry S Oken
Jan 13, 2015·International Journal of Behavioral Development·Margie E LachmanStefan Agrigoroaei
Nov 25, 2017·Aging & Mental Health·Sandi PhibbsMartin J Sliwinski
Oct 10, 2018·Psychosomatic Medicine·Robert S StawskiStuart W S MacDonald
Feb 25, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Andrzej BrodziakAlicja Różyk-Myrta
May 10, 2017·Annual Review of Clinical Psychology·Laura A RabinRebecca E Amariglio
Dec 5, 2019·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Michio MarutaMasahiro Kawagoe
Oct 6, 2020·Journal of Gay & Lesbian Mental Health·Anthony N Correro, Kristy A Nielson
Nov 10, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Nigel P StocksUNKNOWN ASPREE Investigator Group
Feb 11, 2020·Journal of Alzheimer's Disease : JAD·Kaitlin B CasalettoLaura B Zahodne
Dec 31, 2020·International Journal of Environmental Research and Public Health·Shiming LiaoRuoxi Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.