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Mechanisms of glycolytic inhibition in ischemic rat hearts

Circulation Research

Dec 1, 1975

Michael J RovettoJessica Neely

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Abstract

The mechanisms of glycolytic inhibition in ischemic myocardium were investigated in the isolated, perfused rat heart. Glycolysis was inhibited at the level of glyceraldehyde-3-phosphate dehydrogenase. The major factors that accounted for the glycolytic inhibition in the ischemic heart c...read more

Mentioned in this Paper

Extracellular Space
Brain Hypoxia
Glyceraldehyde-3-phosphate dehydrogenase
Perfusion
Rat Heart
Lactates
Lactic Acid Measurement
Blood Flow Velocity
Glycolysis Inhibition
Anhydrous Dextrose
Paper Details
References
    • References12
    • Citations111
    • References12
    • Citations111
  • Mechanisms of glycolytic inhibition in ischemic rat hearts

    Circulation Research

    Dec 1, 1975

    Michael J RovettoJessica Neely

    PMID: 157

    DOI: 10.1161/01.res.37.6.742

    Abstract

    The mechanisms of glycolytic inhibition in ischemic myocardium were investigated in the isolated, perfused rat heart. Glycolysis was inhibited at the level of glyceraldehyde-3-phosphate dehydrogenase. The major factors that accounted for the glycolytic inhibition in the ischemic heart c...read more

    Mentioned in this Paper

    Extracellular Space
    Brain Hypoxia
    Glyceraldehyde-3-phosphate dehydrogenase
    Perfusion
    Rat Heart

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    Paper Details
    References
    • References12
    • Citations111
    • References12
    • Citations111
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