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Mechanisms of glycolytic inhibition in ischemic rat hearts

Circulation Research

Dec 1, 1975

M J RovettoJ R Neely

Abstract

The mechanisms of glycolytic inhibition in ischemic myocardium were investigated in the isolated, perfused rat heart. Glycolysis was inhibited at the level of glyceraldehyde-3-phosphate dehydrogenase. The major factors that accounted for the glycolytic inhibition in the ischemic heart c...read more

Mentioned in this Paper

GAPDH gene
Hydrogen-Ion Concentration
Lactic Acid Measurement
Myocardial Stunning
Metabolic Inhibition
Glycolysis Inhibition
Brain Hypoxia
Intracellular Fluid
Lactates
Hypoxia
1
Paper Details
References
  • References16
  • Citations115
12
  • References16
  • Citations115
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Mechanisms of glycolytic inhibition in ischemic rat hearts

Circulation Research

Dec 1, 1975

M J RovettoJ R Neely

PMID: 157

DOI: 10.1161/01.res.37.6.742

Abstract

The mechanisms of glycolytic inhibition in ischemic myocardium were investigated in the isolated, perfused rat heart. Glycolysis was inhibited at the level of glyceraldehyde-3-phosphate dehydrogenase. The major factors that accounted for the glycolytic inhibition in the ischemic heart c...read more

Mentioned in this Paper

GAPDH gene
Hydrogen-Ion Concentration
Lactic Acid Measurement
Myocardial Stunning
Metabolic Inhibition
Glycolysis Inhibition
Brain Hypoxia
Intracellular Fluid
Lactates
Hypoxia
1

Related Papers

Paper Details
References
  • References16
  • Citations115
12
  • References16
  • Citations115
12345...
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