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Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance

Biochemistry. Biokhimii︠a︡

Aug 1, 2019

Vasily AleshinVictoria I Bunik

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Abstract

Thiamine (vitamin B1) is a precursor of the well-known coenzyme of central metabolic pathways thiamine diphosphate (ThDP). Highly intense glucose oxidation in the brain requires ThDP-dependent enzymes, which determines the critical significance of thiamine for neuronal functions. Howeve...read more

Mentioned in this Paper

Coenzyme Binding
Phosphorylation
Thiamine
Thiamine Triphosphate
Coenzymes
Neuropharmacologic agent
Membrane Transport Proteins
Brain
2-(1-hydroxyethyl)thiamine pyrophosphate
Research
1
3
Paper Details
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Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance

Biochemistry. Biokhimii︠a︡

Aug 1, 2019

Vasily AleshinVictoria I Bunik

PMID: 31522667

DOI: 10.1134/s0006297919080017

Abstract

Thiamine (vitamin B1) is a precursor of the well-known coenzyme of central metabolic pathways thiamine diphosphate (ThDP). Highly intense glucose oxidation in the brain requires ThDP-dependent enzymes, which determines the critical significance of thiamine for neuronal functions. Howeve...read more

Mentioned in this Paper

Coenzyme Binding
Phosphorylation
Thiamine
Thiamine Triphosphate
Coenzymes
1
3
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

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