Mechanisms of Orientation Selectivity in the Primary Visual Cortex

Annual Review of Vision Science
Nicholas J Priebe

Abstract

The mechanisms underlying the emergence of orientation selectivity in the visual cortex have been, and continue to be, the subjects of intense scrutiny. Orientation selectivity reflects a dramatic change in the representation of the visual world: Whereas afferent thalamic neurons are generally orientation insensitive, neurons in the primary visual cortex (V1) are extremely sensitive to stimulus orientation. This profound change in the receptive field structure along the visual pathway has positioned V1 as a model system for studying the circuitry that underlies neural computations across the neocortex. The neocortex is characterized anatomically by the relative uniformity of its circuitry despite its role in processing distinct signals from region to region. A combination of physiological, anatomical, and theoretical studies has shed some light on the circuitry components necessary for generating orientation selectivity in V1. This targeted effort has led to critical insights, as well as controversies, concerning how neural circuits in the neocortex perform computations.

References

Jul 28, 1977·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·D H Hubel, T N Wiesel
Aug 1, 1992·Visual Neuroscience·D J Heeger
Jul 1, 1992·Journal of Neurophysiology·G C DeAngelisR D Freeman
Jan 1, 1991·Vision Research·B C SkottunA B Bonds
May 26, 1988·Nature·Y FrégnacE Bienenstock
Jan 1, 1987·Experimental Brain Research·M C MorroneH D Speed
Jul 1, 1985·Journal of the Optical Society of America. A, Optics and Image Science·J G Daugman
Jul 1, 1974·The Journal of Physiology·B B Boycott, H Wässle
Oct 1, 1974·The Journal of Physiology·P Hammond
Feb 1, 1973·The Journal of Physiology·R M Shapley, D J Tolhurst
May 1, 1973·The Journal of Physiology·P O BishopG H Henry
Nov 1, 1966·The Journal of Physiology·F W Campbell, J J Kulikowski
Feb 29, 1980·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·D Marr, E Hildreth
Oct 22, 1982·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·M C MorroneL Maffei
Nov 10, 1983·The Journal of Comparative Neurology·A G Leventhal, J D Schall
Jan 1, 1982·Experimental Brain Research·G Sclar, R D Freeman
Jul 24, 1980·Nature·W R Levick, L N Thibos
Aug 18, 1995·Science·R J DouglasH H Suarez
Apr 1, 1995·Journal of Neurophysiology·T ShouY Zhou
Apr 25, 1995·Proceedings of the National Academy of Sciences of the United States of America·R Ben-YishaiH Sompolinsky
Jul 1, 1996·Trends in Neurosciences·T R VidyasagarM Volgushev
Dec 6, 1996·Science·C van Vreeswijk, H Sompolinsky
Jul 1, 1997·Neural Computation·G R Holt, C Koch
Sep 1, 1997·Cerebral Cortex·R AzouzD A McCormick
Aug 1, 1997·Current Opinion in Neurobiology·H Sompolinsky, R Shapley
Feb 21, 1998·Journal of Neurophysiology·G A WalkerR D Freeman
Jan 13, 1998·Vision Research·M Carandini, D L Ringach
Jul 4, 1998·Brain Research. Brain Research Reviews·P SomogyiE H Buhl
Aug 11, 1998·Neural Computation·C van Vreeswijk, H Sompolinsky
Oct 20, 1999·Nature Neuroscience·M Riesenhuber, T Poggio

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Citations

Dec 1, 2017·Nature Neuroscience·Michael M Halassa, Sabine Kastner
Apr 26, 2018·Journal of Neurophysiology·Siddhesh SalelkarSupratim Ray
Mar 19, 2019·PLoS Computational Biology·Paul C Bressloff
Jan 25, 2020·Journal of Clinical and Experimental Neuropsychology·Victor WassermanDavid J Libon
Feb 23, 2018·Frontiers in Neural Circuits·Paride Antinucci, Robert Hindges
Jul 5, 2018·Frontiers in Cellular Neuroscience·Xuefeng ShiJianhua Cang
Apr 2, 2019·Frontiers in Neural Circuits·Yanbo LianAnthony N Burkitt
Aug 1, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Ned Block
Feb 28, 2019·Nature Communications·Masoud GhodratiNicholas S C Price
Nov 13, 2020·Nature·L Federico RossiMatteo Carandini
Jun 30, 2021·Nature Communications·Jan H Kirchner, Julijana Gjorgjieva
Jul 25, 2021·Proceedings of the National Academy of Sciences of the United States of America·Lea GoetzMichael Häusser
Dec 1, 2021·Brain Structure & Function·Răzvan Gămănuţ, Daisuke Shimaoka

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