Mechanisms of PhotoBioModulation (PBM) focused on oral mucositis prevention and treatment: a scoping review.

BMC Oral Health
Elodie CourtoisNicolas Magné

Abstract

Oral mucositis (OM) is a severe complication cancer patients undergo when treated with chemoradiotherapy. Photobiomodulation (PBM) therapy also known as low-level laser therapy has been increasingly used for the treatment of such oral toxicity. The aim of this review is to discuss the mechanisms of photobiomodulation (PBM) regarding OM prevention and treatment, and more precisely to focus on the effect of PBM on tumor and healthy cells. MEDLINE/PubMed, and google scholar were searched electronically. Selected studies were focusing on PBM effects on tumor and healthy cells. PBM interactions with the tissue and additional mechanism in OM therapy were detailed in this review. Moreover, this review highlighted a controversy about the carcinogenic effect of PBM. Indeed, Many studies reported that PBM could enhance malignant cell proliferation; suggesting that PBM would have no protective effect. In addition to acting on cancer cells, PBM may damage healthy cells. More prospective studies are needed to assess the effect of PBM on cancer cells in order to improve its use for OM prevention and treatment.

References

Jul 28, 1999·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·R J BensadounF Demard
Apr 20, 2001·Gene·M HüttemannL I Grossman
Jan 5, 2002·Journal of Clinical Laser Medicine & Surgery·H T WhelanJ Caviness
Mar 21, 2002·Journal of Clinical Laser Medicine & Surgery·Antonio Luiz Barbosa PinheiroPedro Soriano da Silva
May 19, 2006·Photomedicine and Laser Surgery·Luigi CortiGuido Sotti
Feb 24, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Nilza Nelly Fontana LopesMaria Teresa Seixas Alves
Feb 23, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Volker Hans SchartingerJózsef Dudás
Dec 1, 2003·Journal of Applied Oral Science : Revista FOB·Renata Lazari SandovalLuciano Lauria Dib
Jun 11, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jan Magnus BjordalRodrigo Ab Lopes-Martins
Jan 1, 2011·Dose-response : a Publication of International Hormesis Society·Ying-Ying HuangMichael R Hamblin
May 26, 2012·Journal of Cellular Physiology·Marco GiannelliLucia Formigli
Aug 3, 2012·Photomedicine and Laser Surgery·Max Myakishev-RempelRaymond Lanzafame
Mar 27, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Kyuseok ChoiWan Hee Kim
Jan 1, 2011·Laser Therapy·R Lubart, H Friedmann
Mar 13, 2014·Cancer·Rajesh V LallaUNKNOWN Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Societ
Apr 3, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sebastiano MercadanteGiampiero Porzio
Dec 17, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Andrei BaraschJames Carroll
Mar 18, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Judith A E M ZechaRené-Jean Bensadoun
Jun 21, 2016·Journal of Biophotonics·Camila Ramos SilvaMartha Simões Ribeiro
Jan 11, 2017·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Lucas Freitas de Freitas, Michael R Hamblin
Jul 10, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Yehuda ZadikUNKNOWN Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (
Aug 9, 2020·Dentistry Journal·Mark CronshawMartin Grootveld

❮ Previous
Next ❯

Citations

Sep 20, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·René-Jean BensadounNicolas Magné
Oct 27, 2021·Photobiomodulation, Photomedicine, and Laser Surgery·Lucas Augusto da Silva, Sérgio Luiz Pinheiro

❮ Previous
Next ❯

Software Mentioned

ISI of Knowledge
Google scholar

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Photomedicine and Laser Surgery
Michael R HamblinJustin R Strahan
BioRxiv : the Preprint Server for Biology
C. M. G. FariaSebastiao Pratavieira
Journal of Investigative and Clinical Dentistry
Padma PandeshwarMahesh B Srinivasreddy
© 2021 Meta ULC. All rights reserved