Mechanisms of starch digestion by α-amylase-Structural basis for kinetic properties

Critical Reviews in Food Science and Nutrition
Sushil DhitalMichael J Gidley

Abstract

Recent studies of the mechanisms determining the rate and extent of starch digestion by α-amylase are reviewed in the light of current widely-used classifications for (a) the proportions of rapidly-digestible (RDS), slowly-digestible (SDS), and resistant starch (RS) based on in vitro digestibility, and (b) the types of resistant starch (RS 1,2,3,4…) based on physical and/or chemical form. Based on methodological advances and new mechanistic insights, it is proposed that both classification systems should be modified. Kinetic analysis of digestion profiles provides a robust set of parameters that should replace the classification of starch as a combination of RDS, SDS, and RS from a single enzyme digestion experiment. This should involve determination of the minimum number of kinetic processes needed to describe the full digestion profile, together with the proportion of starch involved in each process, and the kinetic properties of each process. The current classification of resistant starch types as RS1,2,3,4 should be replaced by one which recognizes the essential kinetic nature of RS (enzyme digestion rate vs. small intestinal passage rate), and that there are two fundamental origins for resistance based on (i) rate-determin...Continue Reading

References

Apr 21, 1979·Lancet·R H Taylor
Nov 1, 1979·Journal of Ultrastructure Research·M YamaguchiD French
May 27, 1978·British Medical Journal·D J JenkinsK G Alberti
Nov 1, 1986·Journal of Animal Science·L W Rooney, R L Pflugfelder
Jul 1, 1985·The British Journal of Nutrition·I E Sambrook, A L Rainbird
Jan 21, 1972·European Journal of Biochemistry·P ElödiM Krysteva
Oct 1, 1981·The American Journal of Clinical Nutrition·K O'DeaP Nestel
Mar 1, 1981·The American Journal of Clinical Nutrition·D J JenkinsD V Goff
Sep 1, 1981·Diabetes Care·D J JenkinsM A Gassull
May 1, 1984·The British Journal of Nutrition·H A JarjisN W Read
Jul 18, 1984·Biochemical and Biophysical Research Communications·E ProdanovG Marchis-Mouren
Apr 1, 1980·The American Journal of Clinical Nutrition·K O'DeaL Antonoff
May 1, 1996·The British Journal of Nutrition·H N EnglystJ H Cummings
Dec 1, 1995·International Journal of Biological Macromolecules·P J Jenkins, A M Donald
Aug 1, 1997·International Journal of Biological Macromolecules·P M BaldwinC D Melia
Jan 30, 1999·The British Journal of Nutrition·C HoeblerJ L Barry
Mar 13, 1999·The American Journal of Clinical Nutrition·K N EnglystJ H Cummings
Apr 21, 1999·Current Opinion in Biotechnology·A G HeyerJ Kossmann
Apr 25, 2000·Journal of Agricultural and Food Chemistry·S ChevallierG Della Valle
May 9, 2001·Biochimica Et Biophysica Acta·S L SlaughterP J Butterworth
Jan 30, 2002·The American Journal of Clinical Nutrition·Katri S JuntunenHannu M Mykkänen
Jan 1, 2003·Journal of Experimental Botany·Alison M SmithSteven M Smith
Jan 28, 2003·Proceedings of the National Academy of Sciences of the United States of America·Buford L NicholsErwin Sterchi
Nov 30, 2004·Biology of the Cell·Athel Cornish-BowdenFlavio Guíñez Abarzúa
Jan 19, 2006·Journal of Agricultural and Food Chemistry·George H RobertsonWilliam J Orts
Mar 22, 2006·The Journal of Nutrition·Cheryl L DikemanGeorge C Fahey
Apr 4, 2006·Journal of Animal Science·G B HuntingtonC J Richards
Nov 10, 2006·Critical Reviews in Food Science and Nutrition·Cheryl L Dikeman, George C Fahey
Nov 14, 2006·Biomacromolecules·Genyi ZhangBruce R Hamaker
Mar 31, 2007·Biomacromolecules·Amparo Lopez-RubioElliot P Gilbert

❮ Previous
Next ❯

Citations

Jan 21, 2016·Food & Function·Sushil DhitalMichael J Gidley
Oct 3, 2015·Carbohydrate Polymers·Bin ZhangMichael J Gidley
Apr 7, 2015·Carbohydrate Polymers·Sushil DhitalFrederick J Warren
May 28, 2016·Critical Reviews in Food Science and Nutrition·Edoardo Capuano
Nov 5, 2016·International Journal of Biological Macromolecules·Qirong KuangXingxun Liu
Apr 1, 2017·Critical Reviews in Food Science and Nutrition·Manuel Gómez, Mario M Martinez
Feb 11, 2018·Journal of the Science of Food and Agriculture·Luis A Bello-PerezJuscelino Tovar
Jul 25, 2018·Critical Reviews in Food Science and Nutrition·José Miguel Aguilera
Jun 22, 2019·Animal : an International Journal of Animal Bioscience·V RatanpaulM J Gidley
Feb 8, 2020·Journal of the Science of Food and Agriculture·Rizliya VisvanathanRamiah Sivakanesan
May 29, 2020·Critical Reviews in Food Science and Nutrition·Ao ShangHua-Bin Li
Jul 22, 2020·Annual Review of Microbiology·Markus Kreuzer, Wolf-Dietrich Hardt
Feb 26, 2019·Critical Reviews in Food Science and Nutrition·Yongxu HanDa-Wen Sun
Jul 27, 2020·Translational Animal Science·Isabella Corsato Alvarenga, Charles G Aldrich
Aug 24, 2018·Nutrients·Isabella Pali-SchöllErika Jensen-Jarolim
Oct 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·José David TorresPedro Bouchon
Jan 7, 2020·Food & Nutrition Research·Yun ZhouYongqiang Cheng
May 18, 2018·MSphere·Frederick J WarrenMichael J Gidley
Nov 30, 2019·Frontiers in Microbiology·Vincenzo CantatoreRaffaella Di Cagno
Jan 8, 2021·Comprehensive Reviews in Food Science and Food Safety·Andrea Pallares PallaresTara Grauwet
Mar 1, 2019·Comprehensive Reviews in Food Science and Food Safety·Haiteng LiSushil Dhital
Dec 17, 2020·Comprehensive Reviews in Food Science and Food Safety·May S M Wee, Christiani Jeyakumar Henry
Dec 18, 2020·Comprehensive Reviews in Food Science and Food Safety·Shujun WangShuo Wang
Jan 15, 2021·Comprehensive Reviews in Food Science and Food Safety·Alessandra Marti, Catrin Tyl
Sep 1, 2018·Comprehensive Reviews in Food Science and Food Safety·Giang T Nguyen, Peter A Sopade

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
in

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.