PMID: 326995Jul 1, 1977Paper

Mechanisms of the flare reaction in human skin

The Journal of Investigative Dermatology
L F Chapman

Abstract

The diffuse area of arteriolar vasodilation surrounding a region of recently injured human skin (axon reflex flare) is dependent upon the integrity of nerve fibers with cell bodies located in dorsal root ganglia. Evidence is presented to indicate that a vasodilator peptide similar to a kinin, neurotensin, or substance P, is implicated in the chain of biochemical events responsible for the transient shift in vascular tonus observable as the flare reaction.

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Citations

Sep 1, 1989·Medical Toxicology and Adverse Drug Experience·B R Lindgren, R G Andersson
Aug 20, 2017·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Steven B Backman
Jan 8, 2020·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jonathan A CohenDaniel H Kaplan
Feb 1, 1989·British Journal of Clinical Pharmacology·J B WarrenC T Dollery
Oct 30, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Jeffrey R ScottNicole S Gibran
Jun 7, 2014·Mediators of Inflammation·Constantin CăruntuEugen Mandache
Feb 1, 1983·Agents and Actions·D F Woodward, D A Owen
May 1, 1991·Pharmacology & Toxicology·U RosenqvistR G Andersson
Apr 5, 2018·Seminars in Immunopathology·João Sousa-Valente, Susan D Brain
May 30, 2021·Journal of Dermatological Science·Sabine AltrichterMarcus Maurer

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