PMID: 7541288Mar 1, 1995Paper

Mechanisms of vascular remodeling in hypertension: role of autocrine-paracrine vasoactive factors

Current Opinion in Nephrology and Hypertension
G H Gibbons

Abstract

The vasculature is an integrated organ capable of modulating its structure in accordance with hemodynamic conditions and locally generated mediators. Vasoactive substances produced within the vasculature are important modulators of vessel structure and vessel tone. This review focuses on the pathogenic role of vasoactive substances in vascular remodeling in hypertension and the potential clinical implications of this pathobiological process. It is speculated that therapeutic strategies that influence vascular remodeling may be clinically more effective.

Citations

Jun 14, 2003·Current Problems in Cardiology·George L Bakris, George A Mensah
Oct 13, 2010·Cardiology Clinics·Mukesh SinghGeorge Bakris
Jul 18, 2002·Cardiology Clinics·George L Bakris, George A Mensah
Sep 17, 2015·Circulation. Heart Failure·William K CornwellBenjamin D Levine
Jan 2, 2015·Circulation Research·Karen Patterson
Jan 15, 1999·Arteriosclerosis, Thrombosis, and Vascular Biology·N SuenobuY Hirata
Jan 13, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·V ShahR J Groszmann
Mar 9, 2010·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Maria Teresa MelgosaJoan Albert Barberà
Feb 15, 2001·The International Journal of Angiology : Official Publication of the International College of Angiology, Inc·Jörg BojungaKlaus Kusterer
Feb 24, 2001·Alimentary Pharmacology & Therapeutics·D Tripathi, P C Hayes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.