Mechanisms that contribute to the tendency to continue chemotherapy in patients with advanced cancer. Qualitative observations in the clinical setting

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Linda BromH Roeline W Pasman

Abstract

The study aims to describe mechanisms that contribute to the tendency towards continuing chemotherapy in patients with advanced cancer. The study conducted qualitative observations of outpatient clinic visits of 28 patients with advanced cancer (glioblastoma and metastatic colorectal cancer). We uncovered four mechanisms in daily oncology practice that can contribute to the tendency towards continuing chemotherapy in patients with advanced cancer: (1) "presenting the full therapy sets the standard"-patients seemed to base their justification for continuing chemotherapy on the "standard" therapy with the maximum number of cycles as presented by the physician at the start of the treatment; (2) "focus on standard evaluation moments hampers evaluation of care goals"-whether or not to continue the treatment was mostly only considered at standard evaluation moments; (3) "opening question guides towards focus on symptoms"-most patients gave an update of their physical symptoms in answer to the opening question of "How are you doing?" Physicians consequently discussed how to deal with this at length, which often took up most of the visit; (4) "treatment is perceived as the only option"-patients mostly wanted to continue with chemothera...Continue Reading

References

Jul 8, 1995·BMJ : British Medical Journal·N Mays, C Pope
Jul 15, 1995·BMJ : British Medical Journal·N Mays, C Pope
Feb 8, 1991·Kennedy Institute of Ethics Journal·D W Brock
Dec 1, 2000·BMJ : British Medical Journal·A M TheG van Der Wal
Jan 10, 2001·Neurology·A C KappelleJ J Heimans
Dec 12, 2003·Cancer·Peter HauAndreas Steinbrecher
Jan 20, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C G KoedootJ C J M de Haes
Mar 11, 2005·The New England Journal of Medicine·Roger StuppUNKNOWN National Cancer Institute of Canada Clinical Trials Group
Dec 3, 2005·The Lancet Oncology·Martin J B TaphoornUNKNOWN National Cancer Institute of Canada Clinical Trials Group
May 2, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Eric Van CutsemRafael G Amado
Sep 25, 2007·Medical Care·Beth Virnig
Aug 9, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Craig C EarleJohn Z Ayanian
Jul 28, 2009·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·V Zietemann, T Duell
Sep 2, 2009·Annals of Internal Medicine·Timothy E QuillAnthony L Back
Feb 4, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jennifer W MackHolly G Prigerson
Jul 10, 2010·Anti-cancer Drugs·Linda J M OostendorpPetronella B Ottevanger
Dec 29, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Joseph A GreerJennifer S Temel
Jan 31, 2012·BMJ : British Medical Journal·A M StiggelboutG Elwyn
Apr 12, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lowell E SchnipperDana S Wollins
Jun 1, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·M FrigeriP Saletti

❮ Previous
Next ❯

Citations

May 20, 2017·Acta Oncologica·Jenny Bergqvist, Peter Strang
May 1, 2021·The American Journal of Hospice & Palliative Care·Larry D CripeLayla B Baker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Family Medicine
Robert E ChristensenLee A Green
Journal of the National Comprehensive Cancer Network : JNCCN
Paul F Engstrom
American Journal of Alzheimer's Disease and Other Dementias
Ronald D AdelmanErika Friedmann
© 2021 Meta ULC. All rights reserved