Mechanistic study of the oxidation of caffeic acid by digital simulation of cyclic voltammograms

Analytical Biochemistry
Hiroki HottaT Osakai

Abstract

The oxidation mechanism of caffeic acid (CAF) has been studied by means of cyclic voltammetry with the plastic formed carbon or glassy carbon electrode. CAF gives a well-developed two-electron reversible wave in acidic media, whereas it shows an irreversible behavior, i.e., a decrease of the rereduction peak, in less acidic media, suggesting that the oxidation of CAF follows an irreversible chemical reaction(s). Digital simulation analyses based on different oxidation mechanisms have been performed for the voltammograms obtained with the GC electrode in 1:1 (v/v) water:ethanol solutions. The results clearly show that the seeming two-electron oxidation of CAF occurs stepwise via one-electron processes, each of which follows an irreversible chemical reaction. It has also been suggested that the semiquinone radical as an intermediate of the one-electron oxidation should play an important role in the oxidation reaction. Evaluations of the rate constants for the chemical reactions have further suggested that the chemical reactions are dimerization reactions.

References

Jan 1, 1996·Free Radical Biology & Medicine·C A Rice-EvansG Paganga
Apr 28, 2001·Biochimica Et Biophysica Acta·H HottaY Tsujino
Jan 1, 1993·Bioscience, Biotechnology, and Biochemistry·J TeraoK Takama

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Citations

Jul 28, 2004·Journal of the American Society for Mass Spectrometry·Ryuichi ArakawaTakashi Kimoto
Dec 17, 2009·Bioelectrochemistry·Slawomir Michalkiewicz, Agata Skorupa
Jul 14, 2007·Analytical Biochemistry·Kaori OtsukaEiichi Tamiya
Sep 27, 2015·Analytical Biochemistry·Mohammad Bagher GholivandHossein Hosseinkhani
Dec 1, 2012·Journal of the Science of Food and Agriculture·Barbara GarciaFátima Paiva-Martins
Nov 12, 2010·Journal of Magnetic Resonance·Xiaocan Zhang, Josef W Zwanziger
Nov 6, 2007·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aleksandra SimićMarija Todorović
Jan 5, 2008·Prikladnaia biokhimiia i mikrobiologiia·K E IakovlevaO V Koroleva
Jan 26, 2021·Journal of Analytical Methods in Chemistry·Georgii S VasylievOlga V Linyucheva
Apr 27, 2010·The Journal of Physical Chemistry. B·Annia GalanoJosé Pedraza-Chaverri
Jan 28, 2010·Journal of Agricultural and Food Chemistry·Jose Luis Munoz-MunozJose Neptuno Rodriguez-Lopez
Apr 8, 2017·Journal of Agricultural and Food Chemistry·Antonio Garcia-JimenezFrancisco García-Cánovas
Apr 9, 2014·Environmental Science & Technology·Elisabeth M-L JanssenKristopher McNeill
May 23, 2013·Journal of Agricultural and Food Chemistry·Olga Makhotkina, Paul A Kilmartin
Nov 20, 2019·Environmental Science & Technology·Edisson SubdiagaStefan B Haderlein

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