Meconium-stained amniotic fluid and meconium aspiration syndrome: a prospective study

Annals of Tropical Paediatrics
Rama Bhat, A Rao

Abstract

The incidence of meconium aspiration syndrome (MAS), associated perinatal factors, morbidity and deaths varies widely. This study aimed to assess the perinatal attributes and morbidity associated with MAS. Over a 2-year period, all neonates born through meconium-stained amniotic fluid (MSAF) were observed for respiratory distress (RD). Birth details, chest radiograph (CXR) and clinical course were documented. Neonates with consistent CXR findings whose RD could not otherwise be explained were defined as MAS. Of 409 neonates born through MSAF, meconium was thick in 196 (47.9%). Fifty-five (13.4%) had RD and 45 (11.3%) were consistent with MAS. Six (1.5%) neonates died. Mean (SD) birthweight and gestation of MAS infants were 2721.9 (510.2) g and 38.67 (1.09) weeks, respectively. About one-third were of low birthweight and 28 were born by caesarean section. On univariate analysis, caesarean delivery, meconium in the trachea and thick meconium were the significant perinatal factors for the development of MAS. On multiple regression analysis, thick meconium was the only independent factor for MAS (OR 7.08, 95% CI 3.08-16.27, p<0.001). An Apgar score of <or=6 and blood gas abnormalities were found in 44.4% and 48.9%, respectively. Ai...Continue Reading

References

Jul 1, 1992·American Journal of Obstetrics and Gynecology·C J MacriR H Paul
Jun 1, 1990·British Journal of Addiction·E LichtensteinD Ary
Nov 1, 1989·American Journal of Obstetrics and Gynecology·E M RossiS C Kalhan
Apr 1, 1989·Ophthalmology·P R Lichter
Apr 1, 1989·British Journal of Obstetrics and Gynaecology·T M ColtartS A Bates
Jan 1, 1994·Annals of Tropical Paediatrics·A S Malik, D Hillman
Mar 1, 1994·American Journal of Obstetrics and Gynecology·P R CialoneJ S Abramowicz
Jul 8, 1998·Pediatric Clinics of North America·G M Cleary, T E Wiswell
Jan 9, 2001·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M M MeydanliA Haberal
Nov 21, 2002·American Journal of Perinatology·William F Liu, Thomas Harrington
May 26, 2004·Pediatric Clinics of North America·Steven L GelfandMichele C Walsh
May 3, 2006·Pediatrics·Peter A DargavilleUNKNOWN Australian and New Zealand Neonatal Network

❮ Previous
Next ❯

Citations

Jun 8, 2013·The Journal of Membrane Biology·Oguz TuncerErcan Kirimi
Aug 19, 2014·Indian Pediatrics·Anthony J B Emmerson
Oct 16, 2010·The Journal of Pediatrics·Peter A DargavilleUNKNOWN lessMAS Trial Study Group
Oct 21, 2015·American Journal of Obstetrics and Gynecology·JoonHo LeeBo Hyun Yoon
Aug 5, 2020·European Journal of Pediatrics·Francesco CavallinDaniele Trevisanuto
Jan 5, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ratchada KitsommartBosco Paes
Feb 18, 2015·Current Opinion in Pediatrics·Usha Krishnan, Erika B Rosenzweig
Aug 19, 2014·Indian Pediatrics·Deepak LouisPraveen Kumar
May 25, 2013·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Mandira DaripaMaria Fernanda B de Almeida
Nov 25, 2020·BMC Pregnancy and Childbirth·Francesco CavallinDaniele Trevisanuto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Perinatology : Official Journal of the California Perinatal Association
Tom E MollnesO D Saugstad
American Journal of Obstetrics and Gynecology
D MosesG Enhorning
Pediatrics
Liling QianChinese Collaborative Study Group for Neonatal Respiratory Diseases
Archives of Disease in Childhood. Fetal and Neonatal Edition
A KarimovaA Goldman
© 2022 Meta ULC. All rights reserved