PMID: 9174451Apr 1, 1997Paper

Medial collateral knee ligament healing. Combined medial collateral and anterior cruciate ligament injuries studied in rabbits

Acta Orthopaedica Scandinavica
S L WooR J Fox

Abstract

We examined the histological appearance and biochemical properties of the healing medial collateral ligament (MCL) of a rabbit knee after combined MCL and anterior cruciate ligament (ACL) injury treated with ACL reconstruction and with or without MCL repair. By so doing, we hoped to understand better our previous bomechanical observations (Ohno et al. 1995) and possibly learn where to focus future investigation into improving the quality of the healing MCL. Ligaments were examined at 6 and 12 weeks of healing. We found healing of all ligaments with hypercellularity and fibroblast elongation along the axis of loading, as expected. Unexpected, however, was the finding of multiple osteophytes in both the repaired and nonrepaired specimens at the medial borders of the joint and at the MCL insertions. These were felt to affect possibly the biomechanics of the MCL by causing stress risers at the point where they undermine the ligament. Biochemically, we demonstrated a correlation between collagen content and hydroxypyridinium crosslinks and modulus of elasticity. While this implies that the modulus is dependent on collagen content and hydroxypyridinium crosslink density, modulus is also probably dependent on other factors such as col...Continue Reading

References

Mar 1, 1992·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R C BrayD D Chimich
Jul 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J A WeissP O Newton
Apr 14, 1988·The New England Journal of Medicine·B Zarins, M Adams
May 1, 1988·The Journal of Bone and Joint Surgery. British Volume·G Laws, M Walton
Nov 1, 1983·The American Journal of Sports Medicine·C FrankW Akeson
Mar 1, 1995·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·C FrankN Shrive
Feb 1, 1995·Journal of Biomechanics·J R MatyasC B Frank
May 1, 1994·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·C P EngleS L Woo
Jan 1, 1995·The Journal of the American Academy of Orthopaedic Surgeons·P A Indelicato
Jan 1, 1994·Archives of Gerontology and Geriatrics·C BattistiA Federico

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Citations

Jun 8, 2002·Journal of Biomechanics·Jeffrey A WeissCarlos Bonifasi-Lista
Jun 1, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Tokifumi MajimaDavid A Hart
May 24, 2007·Tissue Engineering·Ernst HunzikerGordana Vunjak-Novakovic
Aug 13, 2008·Tissue Engineering. Part a·Alejandro J AlmarzaSteven D Abramowitch
Aug 26, 2006·Current Opinion in Obstetrics & Gynecology·Marianna Alperin, Pamela A Moalli
May 22, 2009·Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology : SMARTT·Ho-Joong JungSavio L-Y Woo
Mar 15, 2005·Connective Tissue Research·Jennifer L K MatthewsJohn Robert Matyas
Jun 26, 2003·The Journal of Gene Medicine·Marc JayankuraDavid Klatzmann
Dec 2, 2004·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·S L Y WooS S Chan Saw
Mar 11, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Rui LiangAlejandro Almarza
Jul 23, 2009·Journal of Biomedical Materials Research. Part a·Nick TovarMichael G Dunn
Dec 17, 2014·Journal of Orthopaedic Surgery and Research·Matthew J GermanRachel A Oldershaw
May 30, 2003·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Steven D AbramowitchSavio L-Y Woo
Nov 27, 2009·The American Journal of Sports Medicine·Shilpa M JoshiMartha M Murray
Dec 6, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Volker MusahlSavio L-Y Woo
Jan 18, 2003·Journal of Cellular Biochemistry·Daniel WuDaniel A Grande
Nov 20, 1998·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·B P ChanK M Chan
Dec 19, 2012·The Open Orthopaedics Journal·Giacomo RizzelloVincenzo Denaro
Mar 4, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Rui LiangSteven D Abramowitch
Aug 5, 1998·The American Journal of Sports Medicine·K A HildebrandC C Schmidt
Nov 5, 1999·Clinical Orthopaedics and Related Research·S L WooJ H Wang

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