Medial Rectus Tendon Elongation with Bovine Pericard (Tutopatch®) in Thyroid-Associated Orbitopathy: A Long-Term Follow-Up including Oculodynamic MRI

Journal of Ophthalmology
Monika WipfAnja Palmowski-Wolfe

Abstract

To assess long-term efficacy of bimedial rectus tendon elongation with Tutopatch in thyroid-associated orbitopathy (TAO). Retrospective chart review of 5 patients with TAO undergoing bimedial rectus recession with Tutopatch tendon elongation between 2009 and 2015. We analyzed horizontal squint angles, motility, field of binocular single vision, dose effect of surgery, and when possible oculodynamic MRI (OD-MRI). Dose effect and motility were compared to 4 TAO patients with conventional bimedial recession. In the Tutopatch group, preoperative angles ranged from 14 to 120∆ (prism diopters) at distance and 12-120∆ at near. Mean dose effect was 3.63∆/mm for the distance and 3.43∆/mm for the near angle. All patients were orthotropic at final FU (ranging from 1 to 10 years). OD-MRI showed the elasticity of Tutopatch. In the conventional recession group, preoperative angles ranged between 18 and 35∆ at distance and 12-33∆ at near. At final FU, 2 patients had reverted to their underlying microesotropia <2∆, 1 patient was orthophor, and one was reoperated for a remaining esotropia of 14∆. Dose effect was 2.95∆/mm for the distance and 2.18∆/mm for the near angle. Motility improved in both groups even after 3 months. Dose effect for media...Continue Reading

References

Dec 30, 1999·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·J Esser, A Eckstein
Feb 28, 2004·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A Eckstein, J Esser
Jul 1, 2004·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·H Sprague EustisGeorge Ellis
Jan 11, 2005·European Journal of Ophthalmology·Y WysenbeekA Spierer
Nov 27, 2009·Deutsche medizinische Wochenschrift·K A PontoG J Kahaly
May 29, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·Anja EcksteinJoachim Esser
Oct 10, 2015·European Journal of Ophthalmology·Laurentius J van RijnAnne-Marie E L Langenhorst

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Citations

Sep 20, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Andrea HedergottJulia Fricke

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