Mediastinal cysts with Mullerian differentiation

Respirology Case Reports
Hiroyuki MiuraHiroshi Hirano

Abstract

Mediastinal cysts with Mullerian differentiation are characterized by oestrogen receptor and progesterone receptor positive cell linings. We treated four patients with mediastinal cysts with Mullerian differentiation. All patients were female, from 46 to 52 years old, and had BMIs greater than 26 kg/m2. All but one patient with cough were asymptomatic. The tumours were located in the paravertebral areas around the Th-1-7 vertebrae. There was no left/right difference. All of the preoperative diagnoses were bronchial cysts. Three of the four patients had a history of uterine myoma. Furthermore, antiestrogen therapy was administered to one patient. All of our patients were alive without recurrence for three to eight years after surgery. As long as ectopic epithelia exist, there is a possibility of malignant conversion. Therefore, complete resection of the tumour is necessary.

References

Oct 14, 2004·Virchows Archiv : an International Journal of Pathology·Hideo Hattori
May 4, 2007·The New England Journal of Medicine·Andreas PetterssonOlof Akre
Nov 3, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Adrian P BusingerMarkus Furrer
Nov 21, 2007·Annals of Diagnostic Pathology·Vincent Thomas-de-Montpréville, Elisabeth Dulmet
Oct 1, 2010·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Ronald E BattJohn Yeh
Sep 2, 2011·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Satoru KobayashiMasayuki Chida

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Methods Mentioned

BETA
hormone replacement therapy

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