Mediator of tolerance to abiotic stress ERF6 regulates susceptibility of Arabidopsis to Meloidogyne incognita

Molecular Plant Pathology
Sonja WarmerdamGeert Smant

Abstract

Root-knot nematodes transform vascular host cells into permanent feeding structures to selectively withdraw their nutrients from host plants during the course of several weeks. The susceptibility of host plants to root-knot nematode infections is thought to be a complex trait involving many genetic loci. However, genome-wide association (GWA) analysis has so far revealed only four quantitative trait loci (QTLs) linked to the reproductive success of the root-knot nematode Meloidogyne incognita in Arabidopsis thaliana, which suggests that the genetic architecture underlying host susceptibility could be much simpler than previously thought. Here, we report that, by using a relaxed stringency approach in a GWA analysis, we could identify 15 additional loci linked to quantitative variation in the reproductive success of M. incognita in Arabidopsis. To test the robustness of our analysis, we functionally characterized six genes located in a QTL with the lowest acceptable statistical support and smallest effect size. This led us to identify ETHYLENE RESPONSE FACTOR 6 (ERF6) as a novel susceptibility gene for M. incognita in Arabidopsis. ERF6 functions as a transcriptional activator and suppressor of genes in response to various abioti...Continue Reading

References

Aug 2, 2003·Science·José M AlonsoJoseph R Ecker
Nov 5, 2003·Methods : a Companion to Methods in Enzymology·Gordon K Smyth, Terry Speed
Mar 5, 2004·The Plant Journal : for Cell and Molecular Biology·Oliver ThimmMark Stitt
Apr 14, 2004·The Plant Journal : for Cell and Molecular Biology·Tomasz CzechowskiMichael K Udvardi
Dec 25, 2004·Plant Physiology·Christiane LoefflerMartin J Mueller
Apr 16, 2005·Current Opinion in Biotechnology·Janice de Almeida EnglerPierre Abad
Oct 21, 2005·The Plant Journal : for Cell and Molecular Biology·Fabien JammesBruno Favery
Jan 13, 2006·Plant Physiology·Toshitsugu NakanoHideaki Shinshi
Mar 1, 2006·Current Opinion in Biotechnology·Jianming Yu, Edward S Buckler
Mar 3, 2006·Journal of Experimental Botany·Shisong MaHans J Bohnert
May 26, 2006·Trends in Genetics : TIG·Valerie M Williamson, Amar Kumar
May 3, 2007·BMC Bioinformatics·Marianna ZahurakLeslie Cope
Aug 7, 2007·Nature Genetics·Sung KimMagnus Nordborg
Aug 8, 2007·Journal of Plant Physiology·Marie-Cécile CaillaudBruno Favery
Jun 20, 2008·The New Phytologist·Victoria L FullerPeter E Urwin
Jul 29, 2008·Nature Biotechnology·Pierre AbadPatrick Wincker
Aug 2, 2008·BMC Plant Biology·Jean-Benoit F CharronFathey Sarhan
Dec 17, 2009·The Plant Journal : for Cell and Molecular Biology·Marta BarcalaCarolina Escobar
Dec 17, 2009·BMC Bioinformatics·Christiam CamachoThomas L Madden
Oct 16, 2010·Science·Matthew V RockmanLeonid Kruglyak
Apr 5, 2011·Current Opinion in Plant Biology·Godelieve Gheysen, Melissa G Mitchum
Sep 23, 2011·Molecular Plant-microbe Interactions : MPMI·Geon Hui SonGary Stacey
Dec 6, 2011·Nucleic Acids Research·Philippe LameschEva Huala
Sep 19, 2012·The New Phytologist·Tina KyndtGodelieve Gheysen
Jul 5, 2013·Planta·Tina KyndtJanice de Almeida-Engler
Jul 9, 2014·Annual Review of Phytopathology·Chris C N van Schie, Frank L W Takken
Nov 27, 2014·Frontiers in Plant Science·Bram Van de Poel, Dominique Van Der Straeten
Jul 24, 2015·Genesis : the Journal of Genetics and Development·Tanya Z BerardiniEva Huala
Dec 27, 2017·The Plant Journal : for Cell and Molecular Biology·Geert SmantAska Goverse

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
electrophoresis
dissection
Feature Extraction
PCRs

Software Mentioned

R
Maxwell
MapMan
package
Feature Extraction
rrBLUP
WinRHIZO
REML
EMMA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.