Mediators of anemia in chronic heart failure

Heart Failure Clinics
Thierry H Le Jemtel, Salman Arain

Abstract

Anemia is highly prevalent in patients with chronic heart failure (CHF) and is associated with poor clinical outcome. Increased prevalence of anemia in CHF has been linked to advanced age, female gender, renal function impairment, severity of symptoms, and clinical settings. Overall, the anemia of CHF shares many common features with the anemia of chronic disease. Both impaired iron metabolism and inflammatory stress appear to be the key mediators of the anemia of CHF.

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Aug 25, 2012·Current Heart Failure Reports·Filippos K Triposkiadis, John Skoularigis
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Jun 12, 2020·Current Heart Failure Reports·Andrew XanthopoulosFilippos Triposkiadis

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Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

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