Medical cannabis vs. synthetic cannabinoids: What does the future hold?

Clinical Pharmacology and Therapeutics
D Bolognini, R A Ross

Abstract

The medical use of cannabis has an intricate therapeutic history that finds its roots in ancient China (∼2700 BC). The main psychoactive component of cannabis, Δ(9) -tetrahydrocannabinol (Δ(9) -THC), was discovered in 1964. This was a significant breakthrough, as it allowed the generation of synthetic analogs of Δ(9) -THC, the discovery of cannabinoid receptors, and the generation of synthetic small molecules. Despite this, today there is still a paucity of drugs that target the cannabinoid system.

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Citations

Mar 25, 2015·Clinical Pharmacology and Therapeutics·B Le Foll, R F Tyndale
Nov 18, 2015·BioMed Research International·Andrew M HarrisonMikhail A Dziadzko
Sep 7, 2016·The American Journal of Medicine·Antonia SophocleousStuart H Ralston
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Mar 21, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Astrid Coronado-ÁlvarezEric Murillo-Rodríguez

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