Medical management of osteoporosis and the surgeons' role

Injury
Melvin Paul Rosenwasser, Derly Cuellar

Abstract

Osteoporosis is a worldwide public health issue and with the aging population the resultant increase in fragility fractures has generated a significant socioeconomic impact. Robust scientific research has increased our knowledge of the endocrine mechanisms and pathophysiology of osteoporosis. This information has led to Level 1 randomized clinical trials which demonstrate the beneficial effects of appropriate regimens in reducing the fracture risk and the coincident mortality. Despite these contributions the public health problem remains and has stubbornly failed many public awareness campaigns by governmental and private professional organizations. Effectiveness in delivering the message is greatly enhanced following the sentinel fragility fracture whether it be distal radius, hip, or spine. The treating orthopedic surgeon has the full attention of the injured patient who can be steered into osteoporosis screening programs and ultimately treatment. Studies in Canada have shown that if the surgeon initiates the process by so much as ordering the bone densitometry exam the patient is more likely to get treatment for their underlying disease than if it is just suggested that the patient see their medical doctor at some future dat...Continue Reading

References

Jun 7, 2002·Lancet·Steven R Cummings, L Joseph Melton
Oct 9, 2002·Journal of the American Geriatrics Society·Cynthia L LeibsonL Joseph Melton
Feb 18, 2003·Pharmacotherapy·Sheryl L FollinMichael T McDermott
Jul 25, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Susan B JaglalDave Davis
Oct 14, 2003·The American Journal of Medicine·Daniel H SolomonJerry Avorn
Nov 6, 2003·Annals of Epidemiology·Michael E MussolinoRichard F Gillum
Jul 20, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·V Elliot-GibsonD E Beaton
Jan 5, 2006·The Journal of Bone and Joint Surgery. American Volume·Earl R BogochTimothy M Murray
Apr 28, 2006·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Hasnain M KhandwalaVaneeta K Grover
Sep 20, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·O Johnell, J A Kanis
Apr 11, 2007·Annals of Epidemiology·Elizabeth BassLaurence Z Rubenstein
Jan 4, 2008·The Journal of Bone and Joint Surgery. American Volume·Laura L TosiKenneth J Koval
Nov 4, 2008·The Journal of Bone and Joint Surgery. American Volume·Roberto A MikiDieter M Lindskog
Nov 26, 2009·The Journal of Bone and Joint Surgery. American Volume·Richard M DellKathy Williams
Jan 19, 2010·The Journal of Clinical Endocrinology and Metabolism·Mark J BollandIan R Reid
Jan 28, 2012·International Orthopaedics·Reza Sorbi, Mohamad Reza Aghamirsalim
Oct 19, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A Grey, M J Bolland
Dec 18, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J M QueallyD Bennett
Apr 26, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Dana BliucJacqueline R Center
May 23, 2014·Archives of Osteoporosis·S W WadeC D O'Malley

❮ Previous
Next ❯

Citations

Nov 9, 2017·Cell Transplantation·Denis Dufrane
Apr 11, 2018·Current Osteoporosis Reports·Adam Z KhanAnna N Miller
Dec 19, 2018·Aging Clinical and Experimental Research·Peiwen WangXuedong Yao
Apr 16, 2019·Global Spine Journal·Samuel Pantoja, Marcelo Molina

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Reviews in Musculoskeletal Medicine
Eric M Padegimas, Daniel A Osei
Current Osteoporosis Reports
Luigi Gennari, John P Bilezikian
Current Rheumatology Reports
Luigi Gennari, John P Bilezikian
© 2022 Meta ULC. All rights reserved