Medical management update: Peutz Jeghers syndrome

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Paola HighamEric T Stoopler


Peutz Jeghers syndrome (PJS) is an autosomal dominant disease characterized by hamartomatous polyposis and distinct mucocutaneous pigmentation. PJS is associated with an increased risk for several cancers and other complications such as small intestine intussusception, short bowel syndrome, and anemia. Medical management mainly consists of treatment of the polyps and surveillance. This medical management update will review clinical concepts, therapeutic advances, and emphasize features of PJS important to the oral health care provider.


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