Medical treatment of idiopathic menorrhagia

Journal de gynécologie, obstétrique et biologie de la reproduction
O Graesslin, E Derniaux


Heavy menstrual bleeding is frequent, and can be caused by particular uterine abnormalities such as fibroids or adenomyosis but there is often no recognisable pathology. Surgery such as hysterectomy has proven its efficacy in treating these conditions, but alternatives techniques have been developed since many years and give interesting results. New medical treatments have also emerged, and in particular a new intrauterine levonorgestrel-releasing system (IUD-LNG). In case of dysfunctional uterine bleeding, the use of medical treatment should be considered in first line. Progestogens are often used in this condition even if it has been proven that they are less effective than antifibrinolytics, non steroid anti-inflammatory drugs or IUD-LNG. Appropriate treatment should be considered according to clinical conditions and based on efficacy, tolerance, cost and should also take into account the patient's wishes as observance in case of medical therapy is of particular importance. In case of DUB, medical therapy when correctly prescribed is effective.


Nov 1, 1990·The Australian & New Zealand Journal of Obstetrics & Gynaecology·I S Fraser
Jan 1, 1990·Gynecologic and Obstetric Investigation·Y TsukaharaT Fukuta
Aug 1, 1990·British Journal of Obstetrics and Gynaecology·J M HighamR W Shaw
Jun 1, 1989·Baillière's Clinical Obstetrics and Gynaecology
Feb 1, 1985·American Journal of Obstetrics and Gynecology·G E HofmannJ S Sanfilippo
Jan 1, 1986·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·S G SilverbergTapani Luukkainen
Jun 1, 1985·American Journal of Obstetrics and Gynecology·O Ylikorkala, U M Mäkilä
Oct 24, 1970·British Medical Journal·S T CallenderE Cope
Oct 1, 1995·British Journal of Obstetrics and Gynaecology·L FedeleG Di Nola
Jan 1, 1995·International Journal of Technology Assessment in Health Care·A CoulterM C Rees
May 1, 1995·British Journal of Obstetrics and Gynaecology·J T PrestonS K Smith
Aug 29, 1996·The New England Journal of Medicine·P G Rose
May 1, 1997·European Journal of Gastroenterology & Hepatology·J K Marshall, R H Hunt
Jul 2, 1999·The American Journal of Medicine·J B Raskin
Mar 9, 2000·The Journal of the American Association of Gynecologic Laparoscopists·M G Munro
Oct 21, 2000·Human Reproduction·L A SalamonsenL Lathbury
Nov 21, 2000·Obstetrics and Gynecology·A DavisM Kafrissen
Feb 24, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·A StewartW Phillips
Jan 15, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·U H Winkler
Feb 8, 2002·Obstetrical & Gynecological Survey·David Hubacher, David A Grimes
Feb 28, 2002·Human Reproduction Update·Jason A Abbott, Ray Garry
Oct 18, 2002·Obstetrics and Gynecology·Isabelle CôtéDavid Cumming
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·Stuart A Milne, Henry N Jabbour
Jun 5, 2003·Acta Obstetricia Et Gynecologica Scandinavica·Luis BahamondesCarlos A Petta
Jun 27, 2003·Drugs·Keri Wellington, Antona J Wagstaff
Jul 12, 2003·Biology of Reproduction·Heather A MolendaMarc J Tetel
Jan 24, 2004·The Journal of the American Association of Gynecologic Laparoscopists·Milton H Goldrath
Mar 25, 2004·JAMA : the Journal of the American Medical Association·Miriam KuppermannMs Research Group
Apr 17, 2004·Gynecologic and Obstetric Investigation·Yukoku TamaokaSachiko Ezawa
Nov 24, 2004·The Journal of the American Association of Gynecologic Laparoscopists·Valerio MaisGian B Melis
Jan 18, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Theodoros AgorastosJohn N Bontis
Jan 25, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·C E C KingmanD L Economides
Feb 23, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·H Mactier, L T Weaver
May 24, 2005·The Journal of Steroid Biochemistry and Molecular Biology·Carlo CampagnoliFranco Berrino
Sep 15, 2005·Endocrine Reviews·Henry N JabbourHilary O D Critchley
Feb 21, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·R A BusfieldN Johnson
Oct 31, 2006·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A KriplaniS Diwakar
Nov 16, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Christine DemersSociety of Obstetricians and Gynaecologists of Canada
Feb 1, 2007·Anesthesiology·José Antonio González-CorreaJosé Pedro De La Cruz
Mar 21, 2007·Obstetrical & Gynecological Survey·Anita L Nelson, Stephanie B Teal
Mar 24, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·R F Savaris, R D Braun
Mar 27, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·A KriplaniN Agarwal
Jun 5, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Diana Mansour
Aug 21, 2007·Contraception·Gloria Bachmann, Paul Korner
Sep 22, 2007·Current Opinion in Obstetrics & Gynecology·George Creatsas, Efthimios Deligeoroglou
Apr 11, 2008·Human Reproduction Update·ESHRE Capri Workshop Group
Aug 20, 2008·Expert Opinion on Pharmacotherapy·Johannes C HuberClemens B Tempfer

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