Medical treatment of pericarditis during pregnancy

International Journal of Cardiology
Antonio BrucatoRita Trinchero

Abstract

We have followed 6 pregnancies in women affected by idiopathic pericarditis from 2002 to 2008, the largest reported clinical series. Four women were treated with aspirin 800 mg three times daily; in 3 women aspirin was gradually stopped at 20 weeks gestation, while in one case aspirin was continued till delivery. All the women were treated with prednisone, at low to moderate doses: 4 women with prednisone 10-2.5 mg daily during all the pregnancy, and 2 with prednisone starting from 25 mg daily only during the III trimester. Maternal mean age was 30.2 years, mean gestational age at delivery 38 weeks and mean birth weight 2839 g, with one infant small for gestational age. Five pregnancies were uneventful, while HELLP syndrome developed in the mother in which high-dose aspirin was continued till delivery, with rapid improvement after delivery. All the infants had a good outcome. No recurrences occurred during the pregnancies, while one mother had a recurrence 12 months after delivery, during a mean follow up of 21 months.

References

Feb 1, 1989·American Journal of Obstetrics and Gynecology·W G SimpsonW B Conover
Dec 3, 2008·International Journal of Cardiology·Andrew J S Coats

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Citations

May 5, 2012·Women's Health·Massimo Imazio, Antonio Brucato
Mar 4, 2015·International Journal of Cardiology·Frederick M Howard, Akshar Y Patel
Jul 24, 2015·Hemodialysis International·Fatma Ulku AdamMevlut Koc
Apr 18, 2014·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hirokazu SatoRyota Hokari
Mar 24, 2016·Current Cardiology Reports·Alexander FardmanYehuda Adler
Jan 26, 2016·Journal of Cardiovascular Medicine·Massimo ImazioYehuda Adler
Mar 28, 2012·Current Opinion in Cardiology·Massimo Imazio
Jun 21, 2020·Current Cardiology Reports·Enrico TombettiCarla Carnovale
Oct 28, 2009·Nature Reviews. Cardiology·Massimo ImazioYehuda Adler
Mar 10, 2021·Panminerva Medica·Lisa SeratiAntonio Brucato

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