Medical treatment of recurrent temporomandibular joint dislocation using botulinum toxin A

British Dental Journal
A P Moore, G D Wood

Abstract

This paper describes a new technique for prophylactic treatment of recurrent mandibular dislocation using injection of botulinum toxin A (BtA) into the lateral pterygoid muscles. BtA temporarily weakens muscles by blocking acetylcholine release, and thus operates through a principle different from established treatments such as joint sclerosant therapy, eminectomy or Dautry's procedure. The patient suffered recurrent mandibular dislocations caused by tardive dystonia. We injected 75 mu BtA percutaneously into each lateral pterygoid muscle under electromyographic guidance. No further dislocations occurred over the subsequent 10 months, and follow-up continues. There were no immediate or delayed side effects. More experience is required before this becomes an established treatment. BtA is usually given in outpatients, and is less invasive or destructive than previous options. It may not be suitable if dislocation is due to lax ligaments or weak muscles. Operators must be aware that other BtA preparations require a different dose.

Citations

May 4, 2004·The British Journal of Oral & Maxillofacial Surgery·Peter AquilinaGeoffrey McKellar
Feb 6, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Dolores Martínez-Pérez, Pedro García Ruiz-Espiga
Feb 24, 2001·The Laryngoscope·A Blitzer, L Sulica
Dec 9, 2014·Oral and Maxillofacial Surgery Clinics of North America·Aaron Liddell, Daniel E Perez
Apr 11, 2012·International Journal of Oral and Maxillofacial Surgery·Daniel E Torres, Joseph P McCain
Mar 12, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Olga Vázquez BousoMario Mateos Micas
Dec 5, 2009·International Journal of Oral and Maxillofacial Surgery·O W Majid
Aug 12, 2009·The British Journal of Oral & Maxillofacial Surgery·Kai-Yuan FuXu-Chen Ma
Nov 11, 2008·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Orhan Güven
Mar 18, 2008·Oral and Maxillofacial Surgery Clinics of North America·Reny de Leeuw
Mar 18, 2008·Oral and Maxillofacial Surgery Clinics of North America·Ramesh Balasubramaniam, Saravanan Ram
Feb 12, 2008·The Journal of Prosthetic Dentistry·Tuncer Burak Ozcelik, Zafer Ozgur Pektas
Oct 16, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Johannes M H HenningsThomas C Wetter
Dec 23, 2006·Dental Clinics of North America·Glenn T Clark, Saravanan Ram
Aug 2, 2005·International Journal of Oral and Maxillofacial Surgery·V I UgbokoE T Adebayo
Aug 29, 2006·Cranio : the Journal of Craniomandibular Practice·Kazuya Yoshida, Tadahiko Iizuka
Jun 2, 2015·Journal of Maxillofacial and Oral Surgery·C Sunil DuttManish Pandit
Jun 4, 2016·The British Journal of Oral & Maxillofacial Surgery·Mehmet OztelArthur Bilski
Jul 9, 2016·National Journal of Maxillofacial Surgery·Sanjeev SrivastavaVinit Shah
Aug 1, 2016·Oral and Maxillofacial Surgery Clinics of North America·Glenn T Clark, Saravanan Ram
Nov 23, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Merete BakkeSven Kreiborg
Sep 9, 2017·Journal of Dental Anesthesia and Pain Medicine·Kyung-Soo ParkJung-Woo Lee
Apr 4, 2003·Clinical Oral Investigations·Christoph M ZieglerJ Mühling

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Dolores Martínez-Pérez, Pedro García Ruiz-Espiga
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
R S ChinO R Beirne
© 2021 Meta ULC. All rights reserved