Medication errors with antituberculosis therapy in an inpatient, academic setting: forgotten but not gone

Journal of Clinical Pharmacy and Therapeutics
S P JenA Patrawalla

Abstract

Tuberculosis, an infectious disease caused by the bacteria Mycobacterium tuberculosis, has significant public health implications. Despite the decreasing prevalence of tuberculosis cases and the availability of well-established treatment guidelines, errors with antituberculosis medications remain a concern as clinician experience with the infection has waned and the goal of eradicating tuberculosis has remained unfulfilled. Whereas inappropriate use of other anti-infective classes has been extensively studied, the evaluation of medication errors associated with antituberculosis therapy has been limited to a small number of studies conducted more than two decades ago. This study evaluated the prevalence of inpatient medication errors with antituberculosis therapy in patients with suspected or confirmed tuberculosis disease. All admitted patients treated with at least one antituberculosis medication between July 2010 and June 2013 were evaluated for inclusion in the retrospective study. Multidrug antituberculosis regimens were reviewed for medication errors, which were categorized as dosing errors, drug interactions, omission of therapy and inappropriate continuation of therapy in the presence of drug toxicity. Appropriate manage...Continue Reading

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Citations

Nov 30, 2018·Behavioral Sleep Medicine·Barbara SchwerdtleAngelika Schlarb
Aug 29, 2019·Einstein·Natália Helena de ResendeWânia da Silva Carvalho

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