Medication Management in Frail Older People: Consensus Principles for Clinical Practice, Research, and Education.

Journal of the American Medical Directors Association
Shin J LiauOptimizing Geriatric Pharmacotherapy through Pharmacoepidemiology Network (OPPEN)

Abstract

Frailty is a geriatric condition associated with increased vulnerability to adverse drug events and medication-related harm. Existing clinical practice guidelines rarely provide medication management recommendations specific to frail older people. This report presents international consensus principles, generated by the Optimizing Geriatric Pharmacotherapy through Pharmacoepidemiology Network, related to medication management in frail older people. This consensus comprises 7 principles for clinical practice, 6 principles for research, and 4 principles for education. Principles for clinical practice include (1) perform medication reconciliation and maintain an up-to-date medication list; (2) assess and plan based on individual's capacity to self-manage medications; (3) ensure appropriate prescribing and deprescribing; (4) simplify medication regimens when appropriate to reduce unnecessary burden; (5) be alert to the contribution of medications to geriatric syndromes; (6) regularly review medication regimens to align with changing goals of care; and (7) facilitate multidisciplinary communication among patients, caregivers, and healthcare teams. Principles for research include (1) include frail older people in randomized controlle...Continue Reading

Citations

Oct 4, 2020·The Journal of Nutrition, Health & Aging·I Aprahamian, J E Morley
Jan 25, 2021·Journal of the American Medical Directors Association·Renuka Visvanathan, Solomon Yu
Jun 9, 2021·Aging Clinical and Experimental Research·Pasquale MoneGaetano Santulli
Jul 27, 2021·Current Epidemiology Reports·Heather E Barry, Carmel M Hughes
Aug 28, 2021·European Journal of Clinical Pharmacology·J González-BuenoJ Espaulella-Panicot
Oct 2, 2021·The Senior Care Pharmacist·Shin J Liau, J Simon Bell

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