Medication Regimen Complexity Measured by MRCI: A Systematic Review to Identify Health Outcomes

The Annals of Pharmacotherapy
Vanessa Alves-ConceiçãoDivaldo Pereira de Lyra-Jr

Abstract

To perform a systematic review to identify health outcomes related to medication regimen complexity as measured by the Medication Regimen Complexity Index (MRCI) instrument. Cochrane Library, LILACS, PubMed, Scopus, EMBASE, Open Thesis, and Web of Science were searched from January 1, 2004, until April 02, 2018, using the following search terms: outcome assessment, drug therapy, and Medication Regimen Complexity Index and their synonyms in different combinations. Studies that used the MRCI instrument to measure medication regimen complexity and related it to clinical, humanistic, and/or economic outcomes were evaluated. Two reviewers independently carried out the analysis of the titles, abstracts, and complete texts according to the eligibility criteria, performed data extraction, and evaluated study quality. A total of 23 studies met the inclusion criteria; 18 health outcomes related to medication regimen complexity were found. The health outcomes most influenced by medication regimen complexity were hospital readmission, medication adherence, hospitalization, adverse drug events, and emergency sector visit. Only one study related medication regimen complexity with humanistic outcomes, and no study related medication regimen c...Continue Reading

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Citations

Nov 14, 2019·The Annals of Pharmacotherapy·Vanessa Alves-ConceiçãoDivaldo Pereira de Lyra
May 1, 2020·The Annals of Pharmacotherapy·Colin M CurtainLuke Bereznicki
May 21, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Edward AdinkrahShervin Assari
Feb 20, 2019·Hemodialysis International·Krystina ParkerKnut Stavem
Sep 16, 2020·The Annals of Pharmacotherapy·Mohammad A Al-MamunAndrea Sikora Newsome
May 25, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Kristina S BoyeHiren Patel
Aug 9, 2020·Journal of the Renin-angiotensin-aldosterone System : JRAAS·Joshua J NeumillerKatherine R Tuttle
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Nov 3, 2020·International Journal of Clinical Pharmacy·Shoichi MasumotoJun Hamano
Aug 29, 2019·Medicina clínica·Jesús Díez-Manglano, Lorena Bellostas Muñoz
May 1, 2021·International Journal of Environmental Research and Public Health·Mireia Massot MesquidaPere Torán-Monserrat
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Methods Mentioned

BETA
Pharmacotherapy

Software Mentioned

PRISMA
AMSTAR

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