Medication reminder applications to improve adherence in coronary heart disease: a randomised clinical trial

Heart
Karla SantoJulie Redfern

Abstract

The aim of the MEDication reminder APPs to improve medication adherence in Coronary Heart Disease Study was to evaluate the effectiveness and feasibility of using publicly available high-quality medication reminder applications (apps) to improve medication adherence compared with usual care in patients with coronary heart disease (CHD). An additional aim was to examine whether an app with additional features improved adherence further. Patients with CHD (n=163) were randomised to one of three groups: (1) usual care, (2) a basic app or (3) an advanced app with interactive/customisable features. The primary analysis compared usual care versus app use on the primary outcome of the 8-item Morisky Medication Adherence Scale (MMAS-8) at 3 months. Secondary outcomes included blood pressure and cholesterol levels. The mean age was 57.9 years and 87.7% were male. At 3 months, patients using an app had higher adherence (mean MMAS-8 score 7.11) compared with the usual care group (mean MMAS-8 score 6.63) with a mean difference between groups of 0.47 (95% CI 0.12 to 0.82, p=0.008). There was no significant difference in patients using the basic app versus the advanced app (mean difference -0.16, 95% CI -0.56 to 0.24, p=0.428). There were no...Continue Reading

References

Aug 5, 2005·The New England Journal of Medicine·Lars Osterberg, Terrence Blaschke
May 6, 2008·The Journal of Clinical Hypertension·Donald E MoriskyHarry J Ward
Feb 4, 2009·Current Opinion in Critical Care·Jean-Marie ForelLaurent Papazian
Dec 9, 2010·Circulation. Cardiovascular Quality and Outcomes·Tom G BriffaMatthew Knuiman
Apr 28, 2011·The Annals of Pharmacotherapy·Paul MuntnerMarie Krousel-Wood
Aug 23, 2011·Journal of General Internal Medicine·Ashna D K BowryNiteesh K Choudhry
Jun 29, 2012·Circulation. Cardiovascular Quality and Outcomes·Kate SmolinaMichael J Goldacre
Apr 20, 2013·Journal of Medical Internet Research·Laura DennisonLucy Yardley
Aug 3, 2013·European Heart Journal·Rajiv ChowdhuryOscar H Franco
Jan 23, 2015·The Journal of Allergy and Clinical Immunology. in Practice·Giselle MosnaimLynda H Powell
May 30, 2015·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Nabeel FarooquiDavid Stukus
Mar 24, 2016·Postgraduate Medicine·Helena Anglada-MartínezCarles Codina-Jané
Apr 8, 2016·JMIR MHealth and UHealth·Linda Wilhelmina Maria van KerkhofIngrid Hegger
Jul 28, 2016·Journal of the American Pharmacists Association : JAPhA·Robert B BrowningDavid J Taber

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Citations

Jan 9, 2020·Nursing & Health Sciences·Ali Hussein Alek Al-GanmiLin Perry
Oct 4, 2020·Current Atherosclerosis Reports·Karla Santo, Julie Redfern
Dec 21, 2019·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Yun Shan SuaWenru Wang
Oct 31, 2019·Journal of Managed Care & Specialty Pharmacy·Dominic PaolellaAutumn Zuckerman
Feb 3, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ari LeshnoAlon Skaat
Jan 14, 2021·JMIR MHealth and UHealth·Rebecca ChenMichelle Irving
May 26, 2021·Journal of Medical Internet Research·Shahd Al-ArkeeZahraa Jalal
Aug 13, 2021·BMJ : British Medical Journal·Steven T SimonP Michael Ho
Oct 5, 2020·Internal Medicine Journal·Laura Jiménez-MuñozEnrique Baca-García

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