Medication Review and Patient Outcomes in an Orthopedic Department: A Randomized Controlled Study

Journal of Patient Safety
Marianne LisbyLars Peter Nielsen

Abstract

We investigated the health-related effect of systematic medication review performed by a clinical pharmacist and a clinical pharmacologist on nonelective elderly orthopedic patients. This is a nonblinded randomized controlled study of 108 patients 65 years or older treated with at least 4 drugs. For the intervention, the clinical pharmacist reviewed the participants' medication after completion of the usual medication routine. Information was collected from medical charts, interviews with participants, and database registrations of drug purchase. Results were conferred with the clinical pharmacologist, and recommendations were delivered directly to the ward physicians. The control was usual medication routine, that is, physicians prescribing admitting orders. The primary outcome was time to the first unplanned contact to a physician after discharge (i.e., general practitioner, emergency department visit, or readmission) during 3-month follow-up. Secondary outcomes included other health-related outcomes, for example, length of in-hospital stay, mortality, and quality of life. Time to the first unplanned contact to a physician was 14.9 days (95% confidence interval, 8.9-21.0) in the intervention group compared with 27.3 days (95%...Continue Reading

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Citations

Aug 25, 2015·Basic & Clinical Pharmacology & Toxicology·Eva Aggerholm SaedderBirgitte Brock
Jan 18, 2017·BMC Family Practice·Victor Johan Bernard HuiskesBartholomeus Johannes Fredericus van den Bemt
Dec 5, 2019·Journal of Clinical Pharmacy and Therapeutics·Chengxin XieDong Yin
Nov 29, 2016·British Journal of Clinical Pharmacology·Jean-Baptiste BeuscartAnne Spinewine
Sep 11, 2020·International Journal of Clinical Pharmacy·Godelieve H M PonjeeFatma Karapinar-Çarkit
Mar 29, 2020·BMC Health Services Research·Sophie A KitchenCorinne M Hohl
Dec 10, 2020·European Journal of Hospital Pharmacy. Science and Practice·Thibault VallecilloCéline Mongaret
Feb 13, 2021·Journal of the American Geriatrics Society·Lauren DautzenbergWilma Knol
May 12, 2020·The Journal of Arthroplasty·Sara J HylandMichelle M Lucki
Jul 6, 2021·Journal of General and Family Medicine·Kenya IeSteven M Albert

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