Medication treatment of rheumatoid arthritis with a history of malignancy. Epidemiological data

Zeitschrift für Rheumatologie
M SchmalzingH-P Tony

Abstract

Only insufficient data are available regarding the question whether treatment with immunosuppressants or biologicals is feasible and safe in patients with a history of malignancy. Literature search via PubMed, EULAR abstracts and ACR abstracts from 2013 to 2015. The Société Francaise de Rhumatologie, the Canadian Rheumatology Association and the American College of Rheumatology have tried to make recommendations on this topic. Direct evidence mainly originates from data in three national registries which suggest that treatment with tumor necrosis factor (TNF) inhibitors and rituximab appears to be safe for carefully selected patients, at least if there is a longer interval between treatment with biologicals and oncological treatment. Furthermore, despite partly conflicting data all routine drugs for treating rheumatoid arthritis do not seem to show a consistently increased risk of de novo malignancies. The currently available data are presented for each drug of interest. Taking the current literature into account an attempt is made to formulate an algorithm for the medicinal treatment of patients with rheumatoid arthritis and a history of malignancy.

References

Jan 6, 2007·Annals of the Rheumatic Diseases·G Ruiz-IrastorzaC Aguirre
Feb 27, 2008·Archives of Internal Medicine·Sasha BernatskySamy Suissa
Jun 3, 2008·Arthritis and Rheumatism·Rachelle BuchbinderDamien Jolley
Mar 24, 2011·Current Opinion in Rheumatology·Frank BehrensHarald Burkhardt
Jul 5, 2011·Arthritis Research & Therapy·Katarzyna Elandt, Daniel Aletaha
May 16, 2012·Gastroenterology·Millie D LongMichael D Kappelman
Jul 31, 2012·Annals of the Rheumatic Diseases·Louise Kate MercerUNKNOWN BSRBR Control Centre Consortium
Sep 6, 2012·JAMA : the Journal of the American Medical Association·Maria A Lopez-OlivoMaria E Suarez-Almazor
Oct 12, 2012·Arthritis and Rheumatism·Kevin HaynesUNKNOWN SABER Collaboration
Sep 10, 2013·Seminars in Arthritis and Rheumatism·Daniel H SolomonJeffrey D Greenberg
Nov 15, 2013·Pediatric Rheumatology Online Journal·Michele HooperYessenia Bartley
Aug 12, 2014·Annals of the Rheumatic Diseases·Pauline RaaschouUNKNOWN ARTIS Study Group

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Citations

Aug 26, 2016·Zeitschrift für Rheumatologie·Oliver SanderMatthias Schneider

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