Medication use is associated with fatigue in a sample of community-living individuals who have a spinal cord injury: a chart review

Spinal Cord
A K Y LeeF2N2 Research Group

Abstract

To investigate the relationship between medications known to cause fatigue in spinal cord injury (SCI) and fatigue severity and to describe the pattern of prescription of these medications. Retrospective chart review. GF Strong Rehabilitation Centre, Vancouver, British Columbia, Canada. Medical charts of 136 individuals admitted to the GF Strong Outpatient SCI Program between December 2004 and May 2007 were reviewed. Data collected included information on medications, clinical and demographic characteristics and Fatigue Severity Scale (FSS) scores. Multiple linear regression techniques were used to analyse the data. Fifty-two percent of the subjects had clinically relevant fatigue. As a group, the subjects were taking 147 different medications; 41/147 medications were identified as causing fatigue. The two most commonly prescribed categories of medications were antispasticity medications (75 subjects) and analgesic medications (61 subjects). Although several variables were found to contribute to the FSS scores including the use of fatigue-causing medications, the presence of pain (7.6% of variance) and the use of fatigue-causing analgesics (4.2% of variance) explained the most variance in the scores. Fatigue is prevalent in out...Continue Reading

References

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Citations

Oct 17, 2012·Spinal Cord·I B LidalJ K Stanghelle
Jun 28, 2011·Archives of Physical Medicine and Rehabilitation·Karon F CookMark P Jensen
Feb 1, 2012·Archives of Physical Medicine and Rehabilitation·Lee L Saunders, James S Krause
Apr 22, 2015·Spinal Cord·C F J NooijenUNKNOWN Act-Active Research Group
Oct 9, 2015·The Journal of Spinal Cord Medicine·Tejal PatelJoseph Lee
Jun 29, 2016·Spinal Cord·H A AntonS Forwell
Jan 18, 2018·Topics in Spinal Cord Injury Rehabilitation·Stacy ElliottMarie Carlson
Apr 27, 2019·Frontiers in Neurology·Laura Mordillo-MateosAntonio Oliviero

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