Medications for type 2 diabetes: how will we be treating patients in 50 years?

Diabetologia
Steven E Kahn, John B Buse

Abstract

The past 50 years have seen the development of many new options for treating and preventing type 2 diabetes. Despite this success, the individual and societal burden of the disease continues unabated. Thus, the next 50 years will be critical if we are going to quell the major non-communicable disease of our time. The knowledge we will gain in the next few years from clinical studies will inform treatment guidelines with regard to which agents to use in whom and whether more aggressive approaches can slow the development of hyperglycaemia in those at high risk. Beyond that, we anticipate identification of novel targets and techniques for therapeutic intervention. These advances will lead to more personalised approaches to treatment. Most importantly, we will need to focus our political and economic efforts on enhancing and implementing public health approaches aimed at prevention of diabetes and its co-morbidities. This is one of a series of commentaries under the banner '50 years forward', giving personal opinions on future perspectives in diabetes, to celebrate the 50th anniversary of Diabetologia (1965-2015).

References

Dec 6, 2006·The New England Journal of Medicine·Steven E KahnUNKNOWN ADOPT Study Group
Mar 1, 2012·Journal of the American Medical Informatics Association : JAMIA·Leonard D'AvolioLouis Fiore
May 22, 2013·Diabetes Care·David M NathanUNKNOWN GRADE Study Research Group
Sep 3, 2013·The New England Journal of Medicine·Benjamin M SciricaUNKNOWN SAVOR-TIMI 53 Steering Committee and Investigators
Sep 3, 2013·The New England Journal of Medicine·William B WhiteUNKNOWN EXAMINE Investigators
Jan 7, 2014·Annual Review of Public Health·Edwin B FisherCuirong Xu
Jun 17, 2014·The New England Journal of Medicine·Steven J RussellEdward R Damiano
Oct 11, 2014·Cell·Felicia W PagliucaDouglas A Melton

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