PMID: 3745847Apr 1, 1986Paper

Medium-dose antacids versus cimetidine in the short-term treatment of duodenal ulcer

Journal of Clinical Gastroenterology
G Bianchi PorroE Panza

Abstract

Seventy-eight patients with endoscopically proven duodenal ulcer were randomly allocated to be treated with a medium dose of liquid aluminum-magnesium antacid (75 ml in five daily doses) or cimetidine (400 mg twice daily) for 4 weeks in a prospective double-blind, double-dummy study. Healing rates at completion of trial were 66.7% in the cimetidine-treated group and 71.8% in the antacid group (p, ns). Both treatments were equally effective in relieving ulcer symptoms. Among the patient variables considered, only cigarette smoking was found to have a significant negative effect on ulcer healing. These results indicate that medium doses of antacids are as effective as cimetidine in the short-term treatment of duodenal ulcer.

Citations

Oct 1, 1995·European Journal of Nuclear Medicine·J MonésF Vilardell
Feb 1, 1991·Gut·J MonésF Vilardell
Nov 1, 1986·Scandinavian Journal of Gastroenterology·G Bianchi PorroM Petrillo
Jan 1, 1990·Scandinavian Journal of Gastroenterology. Supplement·G Bianchi Porro, F Parente
Jul 1, 1988·Baillière's Clinical Gastroenterology·S K Lam

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