Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report

Journal of Neurosurgery. Pediatrics
Andrew JeaThomas G Luerssen

Abstract

Multiple metastatic brain tumors and multifocal primary brain tumors of a single histological type have been published in the adult and pediatric literature. However, the simultaneous occurrence of multiple primary brain tumors with different cell types is rare. Even more rare is the pediatric presentation of multiple primary brain tumors with different cell types. The authors describe the case of an 8-year-old boy who presented with a 2-week history of progressive headache, nausea and vomiting, and imbalance. Brain MR imaging demonstrated a heterogeneously enhancing mixed solid/cystic mass of the left cerebellar hemisphere and a larger, midline, more homogeneously enhancing lesion of the superior vermis. Spinal MR imaging was unremarkable. The patient underwent a suboccipital craniotomy and subsequent gross-total resection of both mass lesions. Pathological examination revealed the left cerebellar and superior vermian lesions to be a juvenile pilocytic astrocytoma and a medulloblastoma, respectively. The patient did well in the immediate postoperative period, was discharged home, and underwent neurooncological follow-up. To the best of the authors' knowledge, they describe the first known pediatric case in which a medulloblast...Continue Reading

References

Nov 1, 1978·Journal of Neurology, Neurosurgery, and Psychiatry·R G Robinson
Oct 1, 1977·Cancer·B S Schoenberg
Oct 1, 1976·Journal of Neurosurgery·A J StrongB P O'Neill
May 1, 1975·Journal of Neurology, Neurosurgery, and Psychiatry·P J Wilson, D J Ashley
Sep 1, 1990·Neurosurgery·H Z GökalpS Naderi
Aug 1, 1987·Journal of Neurosurgery·V KasantikulS Wangsuphachart
Jan 1, 1986·Neurology·B L MariaM D Wharam
Jun 1, 1971·Journal of Neurosurgery·S Shuangshoti, M G Netsky
Jan 1, 1974·Neuroradiology·J F Sackett Songsirikul
Nov 1, 1974·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·L E Swischuk, R N Bryan
Oct 1, 1969·Annals of Internal Medicine·F P Li, J F Fraumeni
Jan 1, 1981·Neurosurgery·H G Deen, E R Laws
Jan 1, 1983·Acta neurochirurgica·E ReichenthalJ Israeli
Jan 1, 1984·Surgical Neurology·J F Schnegg, N de Tribolet
May 1, 1961·Neurology·M J MADONICKR M TORACK
Feb 1, 1963·Journal of Neurosurgery·U BATZDORF, N MALAMUD
Jul 1, 2005·Neurosurgery·Sean A McNattJ Gordon McComb
Oct 21, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Lester LeeTibor Hortobágyi
Jan 1, 1948·Journal of Neuropathology and Experimental Neurology·W S ALEXANDER
May 1, 1947·Journal of Neurosurgery·E H FEIRING, L M DAVIDOFF
Jan 1, 1945·Journal of Neuropathology and Experimental Neurology·W R KIRSCHBAUM

❮ Previous
Next ❯

Citations

Aug 5, 2015·Journal of Pediatric Hematology/oncology·Kamon PhuakpetEric Bouffet
Aug 22, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nisreen AmayiriEric Bouffet

❮ Previous
Next ❯

Related Concepts

Related Feeds

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.