PMID: 517184Jan 1, 1979Paper

Medulloblastoma in childhood

Acta neurochirurgica
A J Raimondi, T Tomita

Abstract

Fifty-one patients with medulloblastoma have been treated at the Children's Memorial Hospital during the past 11 years. The ratio between males and females was 2:1. The ages ranged from 4 months to 12 years; 7 patients were less than 12 months old at the time of diagnosis. After 1969, prior to definitive surgery, all patients were given a ventriculo-peritoneal shunt to decompress the hydrocephalus which was invariably present. There were no cases of systemic metastasis related to these shunts. Subsequently, posterior fossa craniotomy was performed, with total or radical resection of tumour in 13 cases, subtotal resection in 20 cases, and partial resection or biopsy in 14 cases. After completion of surgical treatment and radiotherapy, the three-year survival rate was 45.6 per cent and the five-year survival 34.5 per cent. The survival of children given total resection of the tumour was significantly longer, and females survived longer than males. Local recurrence and spinal cord or systemic metastases are discussed. Reexploration of the posterior fossa for recurrences failed to improve the prognosis. Recurrent or metastatic medulloblastoma should be treated by radiotherapy or chemotherapy, or both.

References

Jan 1, 1977·Journal of Neurosurgery·J Mealey, P V Hall
Apr 1, 1977·Acta Radiologica: Therapy, Physics, Biology·S Das, J E Dalby
Jan 1, 1975·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·G A King, R H Sagerman
May 1, 1976·Journal of Neurosurgery·H J HoffmanR P Humphreys
Jan 1, 1970·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·J StolzenbergM M Kligerman
Mar 30, 1974·British Medical Journal·H W Ward
Feb 1, 1972·The Journal of Small Animal Practice·D W Christie, E T Bell
May 1, 1973·Radiology·P Brutschin, G J Culver
May 1, 1973·Radiology·J W Debnam, T W Staple
Jun 1, 1972·Journal of Neurosurgery·N C GonzalezJ A Maxwell
Jul 1, 1972·Archives of Neurology·T A NewkirkJ L Reinglass
Oct 1, 1969·The Journal of Pathology·D J DaviesC Roberts
May 1, 1970·Neurology·D S FaustE L Mancall
Mar 1, 1969·The British Journal of Radiology·D R McFarlandG K Bahr
Jan 1, 1969·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·H J BloomJ M Henk
Jun 1, 1961·Brain : a Journal of Neurology·E PATERSON
Jul 1, 1959·The Journal of Pathology and Bacteriology·L J RUBINSTEIN
Jan 1, 1953·The Journal of the Faculty of Radiologists·J J RICHMOND

❮ Previous
Next ❯

Citations

Jan 1, 1987·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M K Neidhardt, C C Bailey
Jan 1, 1987·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M ColangeloA Ambrosio
Feb 1, 1996·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S PezzottaE Madon
Jan 1, 1982·Acta neurochirurgica·W MüllerN Klug
Jun 1, 1981·International Journal of Radiation Oncology, Biology, Physics·H W Chin, Y Maruyama
Jan 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·S RochkindY Goldhammer
Jan 2, 2010·Journal of Neurosurgery. Pediatrics·Kristophe J KaramiSandeep Sood
Oct 1, 1984·Journal of Neurosurgery·J R FarwellJ T Flannery
Jan 1, 1985·Acta neurochirurgica·O Heiskanen, J Lehtosalo
Jan 1, 1990·British Journal of Neurosurgery·R Patir, A K Banerji
Feb 6, 2010·International Journal of Radiation Oncology, Biology, Physics·Ali MazloomArnold C Paulino
Oct 1, 1986·International Journal of Radiation Oncology, Biology, Physics·B W HershatterE B Cox
Nov 1, 1987·International Journal of Radiation Oncology, Biology, Physics·W N BrandR P Tokars
Dec 1, 1985·Surgical Neurology·O Al-MeftyJ L Fox
Feb 13, 2001·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·P E Clayton, C T Cowell
Aug 1, 1992·Cancer·S ItoM S Edwards
Nov 1, 1995·Neurosurgery·F Van CalenberghP Casaer
Sep 15, 1985·Cancer·S McIntoshJ L Venes
Nov 1, 1984·Cancer·F F BellaniG Nicola
Jul 15, 1986·Cancer·P K Duffner, M E Cohen
Nov 1, 1981·Medical & Biological Engineering & Computing·P LövsundP A Oberg
Jan 1, 1987·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·R Rivera-LunaG Martínez-Guerra
Feb 1, 1995·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·L Cervoni, G Cantore
Dec 1, 1990·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·A UozumiN Arimizu
Mar 1, 1994·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M BenassiV Valentino
Jan 1, 1986·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·J E KingstonN J Garvan
Jan 1, 1987·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·J Gómez PerúnT Arana

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.